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Cation-independent M6PR (IGF2R) (AB2849) Rabbit mAb
Cation-independent M6PR (IGF2R) (AB2849) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M0445
Species Reactivity:Human,Mouse,Rat
Application:WB,IF/ICC,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
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Recombinant Antibody
20 ul Size Available
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Cation-independent M6PR (IGF2R) (AB2849) Rabbit mAb

Confocal imaging of NIH/3T3 cells using Cation-independent M6PR (IGF2R) Rabbit mAb (M0445, dilution 1:100) (Red).The cells were counterstained with α-Tubulin Mouse mAb (W0051, dilution 1:400) (Green).DAPI was used for nuclear staining (blue).Objective: 100x.

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Product Details
Product Name
Cation-independent M6PR (IGF2R) (AB2849) Rabbit mAb
Description
This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele; however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611) .
Catalog No
M0445
Species Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Host
Rabbit
Modifcation
Unmodified
Clone
AB2849
Isotype
IgG
Application
WB, IF/ICC, ELISA
Application Dilutions
WB, 1:1000-1:2000 | IF/ICC, 1:100-1:1000 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 2392 - 2491 of human Cation - independent M6PR (IGF2R).
Specificity
This antibody detects endogenous levels of Cation-independent M6PR (IGF2R) protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.02% sodium azide.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
IGF2R
Gene ID
3482
Human swiss
P11717
Protein Name
Cation-independent M6PR (IGF2R)
Synonyms
MPR1; MPRI; CD222; CIMPR; M6P-R; MPR300; CI-M6PR; MPR 300; M6P/IGF2R; Cation-independent M6PR (IGF2R)
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Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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