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Histone H3 (Mono Methyl Arg2) (AB3741) Rabbit mAb
Histone H3 (Mono Methyl Arg2) (AB3741) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M0385
Species Reactivity:Human,Mouse,Rat,Other (Wide Range Predicted)
Application:WB,DB,ELISA,CUT&Tag
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
Product Details
Product Name
Histone H3 (Mono Methyl Arg2) (AB3741) Rabbit mAb
Description
This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs) , act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
Catalog No
M0385
Species Reactivity
Human, Mouse, Rat, Other (Wide Range Predicted)
Clonality
Monoclonal
Host
Rabbit
Modifcation
MonoMethyl R2
Clone
AB3741
Isotype
IgG
Application
WB, DB, ELISA, CUT&Tag
Application Dilutions
WB, 1:500-1:1000 | DB, 1:500-1:1000 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. | CUT&Tag, 10⁵ cells /1 μg
Immunogen
A synthetic monomethylated peptide around R2 of human Histone H3 (Q16695).
Specificity
The antibody detects endogenous levels of Histone H3 protein only when mono-methylated at Arg2. The antibody does not cross-react with di-methylated or tri-methylated Histone H3 Arg2 and other mono-methylated sites.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.02% sodium azide.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
Histone H3
Gene ID
8290; 8350
Human swiss
Q16695; P68431
Protein Name
Histone H3 (Mono Methyl Arg2)
Synonyms
H3/A; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3FA; H3C10; H3C11; H3C12; HIST1H3A; MonoMethyl-Histone H3-R2
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