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Primary Antibodies
STAT1 (AB4953) Rabbit mAb
STAT1 (AB4953) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M0350
Species Reactivity:Human,Mouse,Rat
Application:WB,IP,ELISA,ChIP-seq
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
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Recombinant Antibody
20 ul Size Available
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STAT1 (AB4953) Rabbit mAb

Chromatin immunoprecipitation was performed with 35 μg of cross-linked chromatin from HeLa cells treated by TNF-α (30ng/ml, 1h) using 5 μg of STAT1 Rabbit mAb (M0350).The ChIP sequencing results indicate the enrichment pattern of STAT1 across chromosome 6 (upper panel) and the genomic region encompassing TAP1, a representative gene enriched in STAT1 (lower panel).

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Product Details
Product Name
STAT1 (AB4953) Rabbit mAb
Description
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo-or heterodimers that translocate to the cell nucleus where they act as transcription activators. The protein encoded by this gene can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. The protein plays an important role in immune responses to viral, fungal and mycobacterial pathogens. Mutations in this gene are associated with Immunodeficiency 31B, 31A, and 31C.
Catalog No
M0350
Species Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Host
Rabbit
Modifcation
Unmodified
Clone
AB4953
Isotype
IgG
Application
WB, IP, ELISA, ChIP-seq
Application Dilutions
WB, 1:1000-1:6000 | IP, 0. 5μg-4μg antibody for 200μg-400μg extracts of whole cells | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. | ChIP-seq, 1:50-1:200
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1 - 100 of human STAT1.
Specificity
This antibody detects endogenous levels of STAT1 protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.02% sodium azide.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
STAT1
Gene ID
6772
Human swiss
P42224
Protein Name
STAT1
Synonyms
CANDF7; IMD31A; IMD31B; IMD31C; ISGF-3; STAT91; STAT1
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Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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