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GDNF Receptor alpha 1/GFRA1 (AB3585) Rabbit mAb
GDNF Receptor alpha 1/GFRA1 (AB3585) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M0201
Species Reactivity:Human,Mouse,Rat
Application:IF/ICC,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
Product Details
Product Name
GDNF Receptor alpha 1/GFRA1 (AB3585) Rabbit mAb
Description
This gene encodes a member of the glial cell line-derived neurotrophic factor receptor (GDNFR) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature receptor. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. This receptor is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.
Catalog No
M0201
Species Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Host
Rabbit
Modifcation
Unmodified
Clone
AB3585
Isotype
IgG
Application
IF/ICC, ELISA
Application Dilutions
IF/ICC, 1:100-1:400 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 361 - 460 of human GDNF Receptor alpha 1/GFRA1.
Specificity
This antibody detects endogenous levels of GDNF Receptor alpha 1/GFRA1 protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.09% Sodium azide.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
GFRA1
Gene ID
2674
Human swiss
P56159
Protein Name
GDNF Receptor alpha 1/GFRA1
Synonyms
GDNFR; RET1L; RETL1; RHDA4; TRNR1; GDNFRA; GFRalpha-1; GFR-ALPHA-1; GDNFR-alpha-1
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