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Primary Antibodies
ELN (AB3389) Rabbit mAb
ELN (AB3389) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M0183
Species Reactivity:Human
Application:WB,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
# Datasheet #
# SDS #
Recombinant Antibody
20 ul Size Available
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ELN (AB3389) Rabbit mAb

Western blot analysis of various lysates using ELN Rabbit mAb (M0183) at 1:58000 dilution incubated overnight at 4℃.|Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (SA0002) at 1:10000 dilution.|Lysates/proteins: 25 μg per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Enhanced Kit.|Negative control (NC) : U-937|Exposure time: 60s.

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Product Details
Product Name
ELN (AB3389) Rabbit mAb
Description
This gene encodes a protein that is one of the two components of elastic fibers. Elastic fibers comprise part of the extracellular matrix and confer elasticity to organs and tissues including the heart, skin, lungs, ligaments, and blood vessels. The encoded protein is rich in hydrophobic amino acids such as glycine and proline, which form mobile hydrophobic regions bounded by crosslinks between lysine residues. Degradation products of the encoded protein, known as elastin-derived peptides or elastokines, bind the elastin receptor complex and other receptors and stimulate migration and proliferation of monocytes and skin fibroblasts. Elastokines can also contribute to cancer progression. Deletions and mutations in this gene are associated with supravalvular aortic stenosis (SVAS) and autosomal dominant cutis laxa.
Catalog No
M0183
Species Reactivity
Human
Clonality
Monoclonal
Host
Rabbit
Modifcation
Unmodified
Clone
AB3389
Isotype
IgG
Application
WB, ELISA
Application Dilutions
WB, 1:20000-1:60000 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 27 - 200 of human ELN.
Specificity
This antibody detects endogenous levels of ELN protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.09% Sodium azide.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
ELN
Gene ID
2006
Human swiss
P15502
Protein Name
ELN
Synonyms
WS; WBS; SVAS; ADCL1
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Catalog No: SA0002

HRP* Goat Anti Rabbit IgG(H+L)

Price/Quantity:
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Size:
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Publications (18)
Melatonin treatment improves human umbilical cord mesenchymal stem cell therapy in a mouse model of type II diabetes mellitus via the PI3K/AKT signaling pathway. Stem Cell Research & Therapy2022 Dec;13(1):1-15. Human,Mouse liver tissue hUC-MSC

Author: Available in link provided

Date of Publication : Available in link provided

Calcium‐binding protein 39 promotes hepatocellular carcinoma growth and metastasis by activating extracellular signal‐regulated kinase signaling pathway. HEPATOLOGY 2017 Sep 29 WB Human LO2 cell, QGY-7703 cell, 97H cell, Huh7 cell

Author: Available in link provided

Date of Publication : Available in link provided

Nucleus-targeting near-infrared nanoparticles based on TAT peptide-conjugated IR780 for photo-chemotherapy of breast cancer. CHEMICAL ENGINEERING JOURNAL Chem Eng J. 2020 Jan;380:122458 WB Mouse 1:100 4T1 tumor 4T1 cell

Author: Available in link provided

Date of Publication : Available in link provided

Regulation of proliferation and cell cycle by protein regulator of cytokinesis 1 in oral squamous cell carcinoma. Cell Death & Disease 2018 May 11 WB Human,Mouse 1:200 oral squamous cell carcinoma (OSCC) tissue, HSC-2 cell-xenograft

Author: Available in link provided

Date of Publication : Available in link provided

miR-125a-5p inhibits tumorigenesis in hepatocellular carcinoma. Aging-US Aging-Us. 2019 Sep 30; 11(18): 7639–7662 WB Mouse Bel-7404 cell-xenograft

Author: Available in link provided

Date of Publication : Available in link provided

Resveratrol inhibits monocrotaline-induced pulmonary arterial remodeling by suppression of SphK1-mediated NF-κB activation. LIFE SCIENCES Life Sci. 2018 Oct;210:140 IHC Rat 1:200 lung PASMCs

Author: Available in link provided

Date of Publication : Available in link provided

Growth suppressive effect of pegylated arginase in malignant pleural mesothelioma xenografts. RESPIRATORY RESEARCH 2017 May 02 WB Human 211H cell, H226 cell

Author: Available in link provided

Date of Publication : Available in link provided

Reg3A (regenerating family member 3 alpha) acts as a tumor suppressor by targeting DMBT1 (deleted in malignant brain tumors 1) in gastric cancer. Bioengineered Bioengineered. 2021;12(1):7644-7655 WB Human 1:1000 AGS cell

Author: Available in link provided

Date of Publication : Available in link provided

Targeting FoxM1 by thiostrepton inhibits growth and induces apoptosis of laryngeal squamous cell carcinoma. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY 2014 Nov 13 IHC Mouse LSCC xenograft

Author: Available in link provided

Date of Publication : Available in link provided

Huaier Restrains Proliferative and Migratory Potential of Hepatocellular Carcinoma Cells Partially Through Decreased Yes-Associated Protein 1. Journal of Cancer J Cancer. 2017; 8(19): 4087–4097 WB Human Bel-7404 cell,SMMC-7721 cell

Author: Available in link provided

Date of Publication : Available in link provided

Zhang, Hong, et al. "Therapeutic potential of bixin in PM2. 5 particles-induced lung injury in an Nrf2-dependent manner." Free Radical Biology and Medicine 126 (2018): 166-176.

Author: Available in link provided

Date of Publication : Available in link provided

Duan, Liang, et al. "S100A6 stimulates proliferation and migration of colorectal carcinoma cells through activation of the MAPK pathways." International journal of oncology 44.3 (2014): 781-790.

Author: Available in link provided

Date of Publication : Available in link provided

Zhu, Yanting, et al. "COP9 signalosome subunit 6 mediates PDGF-induced pulmonary arterial smooth muscle cells proliferation." Experimental cell research 371.2 (2018): 379-388.

Author: Available in link provided

Date of Publication : Available in link provided

GILT in tumor cells improves T cell-mediated anti-tumor immune surveillance. IMMUNOLOGY LETTERS Immunol Lett. 2021 Jun;234:1 WB Mouse 1 : 500 MC38 cell

Author: Available in link provided

Date of Publication : Available in link provided

Potential Chemoprevention of Paeoniflorin in Colitis-associated Colorectal Cancer by Network Pharmacology, Molecular Docking, and In Vivo Experiment CHEMISTRY & BIODIVERSITY Xingming Ma IHC Mouse

Author: Available in link provided

Date of Publication : Available in link provided

Integrated metabolomics and phosphoproteomics reveal the protective role of exosomes from human umbilical cord mesenchymal stem cells in naturally aging mouse livers EXPERIMENTAL CELL RESEARCH Yanqiu Xing IF Mouse hepatic

Author: Available in link provided

Date of Publication : Available in link provided

Antitumor effect of luteolin proven by patient-derived organoids of gastric cancer. Shigang Ding IHC Human 1:300 gastric cancer (GC) tissue,patient-derived organoids (PDOs)

Author: Available in link provided

Date of Publication : Available in link provided

NCX1/Ca2+ promotes autophagy and decreases bortezomib activity in multiple myeloma through non-canonical NFκB signaling pathway Cell Communication and Signaling Li Tingting IHC Human,Mouse 1:100 MM cell-xenograft,bone marrow (BM) tissue

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

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    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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