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Primary Antibodies
Tyrosinase (AB5147) Rabbit mAb
Tyrosinase (AB5147) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M0145
Species Reactivity:Human
Application:IF/ICC,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
# Datasheet #
# SDS #
Recombinant Antibody
20 ul Size Available
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Tyrosinase (AB5147) Rabbit mAb

Confocal imaging of paraffin-embedded Human malignant melanoma tissue using Tyrosinase Rabbit mAb (M0145, dilution 1:200) followed by a further incubation with Cy3 Goat Anti-Rabbit IgG (H+L) (SA1138, dilution 1:500) (Red).DAPI was used for nuclear staining (Blue).Objective: 40x.Perform high pressure antigen retrieval with 0.01 M citrate buffer (pH 6.0) prior to IF staining.

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Product Details
Product Name
Tyrosinase (AB5147) Rabbit mAb
Description
The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.
Catalog No
M0145
Species Reactivity
Human
Clonality
Monoclonal
Host
Rabbit
Modifcation
Unmodified
Clone
AB5147
Isotype
IgG
Application
IF/ICC, ELISA
Application Dilutions
IF/ICC, 1:50-1:200 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 200 - 300 of human Tyrosinase.
Specificity
This antibody detects endogenous levels of Tyrosinase protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% proclin300.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
TYR
Gene ID
7299
Human swiss
P14679
Protein Name
Tyrosinase
Synonyms
ATN; CMM8; OCA1; OCA1A; OCAIA; SHEP3; Tyrosinase
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