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PKM2-specific (AB4570) Rabbit mAb
PKM2-specific (AB4570) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M0045
Species Reactivity:Human,Mouse,Rat
Application:WB,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
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Recombinant Antibody
20 ul Size Available
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PKM2-specific (AB4570) Rabbit mAb

Western blot analysis of various lysates, using PKM2-specific Rabbit mAb (M0045) at 1:1000 dilution.|Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (SA0002) at 1:10000 dilution.|Lysates/proteins: 25μg per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit.|Exposure time: 30s.

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Product Details
Product Name
PKM2-specific (AB4570) Rabbit mAb
Description
This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported.
Catalog No
M0045
Species Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Host
Rabbit
Modifcation
Unmodified
Clone
AB4570
Isotype
IgG
Application
WB, ELISA
Application Dilutions
WB, 1:1000-1:4000 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 380 - 480 of human PKM2 - specific.
Specificity
This antibody detects endogenous levels of PKM2-specific protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% proclin300.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
PKM
Gene ID
5315
Human swiss
P14618
Protein Name
PKM2-specific
Synonyms
PK3; TCB; p58; OIP3; PKM2; CTHBP; THBP1; HEL-S-30; PKM2-specific
Related Products

Catalog No: SA0001

HRP* Goat Anti Mouse IgG(H+L)

Price/Quantity:
$50

Size:
100μL

Catalog No: SA0002

HRP* Goat Anti Rabbit IgG(H+L)

Price/Quantity:
$50

Size:
100μL

Publications (6)
Mitochondrial separation protein inhibitor inhibits cell apoptosis in rat lungs during intermittent hypoxia. Experimental and Therapeutic Medicine 2019 Mar 01 WB Human,Rat 1:1000 lung WRTL1 cell

Author: Available in link provided

Date of Publication : Available in link provided

miR-34a/DRP-1-mediated mitophagy participated in cisplatin-induced ototoxicity via increasing oxidative stress BMC Pharmacology & Toxicology Haidi Yang WB Mouse cochlear tissue HEI-OC1 cell

Author: Available in link provided

Date of Publication : Available in link provided

PIM1 attenuates cisplatin-induced AKI by inhibiting Drp1 activation CELLULAR SIGNALLING Yuzhen Li WB Mouse 1:1000 kidney tissue mouse proximal tubular cell

Author: Available in link provided

Date of Publication : Available in link provided

ALCAT1-mediated abnormal cardiolipin remodelling promotes mitochondrial injury in podocytes in diabetic kidney disease Cell Communication and Signaling Hao Yiqun WB Human,Mouse 1:1000 glomerulus tissue podocytes

Author: Available in link provided

Date of Publication : Available in link provided

Human umbilical cord-derived mesenchymal stem cells ameliorate liver fibrosis by improving mitochondrial function via Slc25a47-Sirt3 signaling pathway BIOMEDICINE & PHARMACOTHERAPY Ping Chen IF Mouse liver tissue

Author: Available in link provided

Date of Publication : Available in link provided

Non-cytopathic bovine viral diarrhea virus (BVDV) inhibits innate immune responses via induction of mitophagy VETERINARY RESEARCH Li Zhijun WB Bovine MDBK cell

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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