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Serotonin transporter (AB4852) Rabbit mAb
Serotonin transporter (AB4852) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M0037
Species Reactivity:Human,Rat
Application:WB,IF/ICC,IP,ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
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Recombinant Antibody
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Serotonin transporter (AB4852) Rabbit mAb

Confocal imaging of paraffin-embedded Human liver cancer tissue using Serotonin transporter Rabbit mAb (M0037, dilution 1:200) followed by a further incubation with Cy3 Goat Anti-Rabbit IgG (H+L) (SA1138, dilution 1:500) (Red).DAPI was used for nuclear staining (Blue).Objective: 40x.Perform high pressure antigen retrieval with 0.01 M citrate buffer (pH 6.0) prior to IF staining.

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Product Details
Product Name
Serotonin transporter (AB4852) Rabbit mAb
Description
This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake. There have been conflicting results in the literature about the possible effect, if any, that this polymorphism may play in behavior and depression.
Catalog No
M0037
Species Reactivity
Human, Rat
Clonality
Monoclonal
Host
Rabbit
Modifcation
Unmodified
Clone
AB4852
Isotype
IgG
Application
WB, IF/ICC, IP, ELISA
Application Dilutions
WB, 1:500-1:1000 | IF/ICC, 1:50-1:200 | IP, 0. 5μg-4μg antibody for 400μg-600μg extracts of whole cells | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1 - 100 of human Serotonin transporter.
Specificity
This antibody detects endogenous levels of Serotonin transporter protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.02% sodium azide.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
SLC6A4
Gene ID
6532
Human swiss
P31645
Protein Name
Serotonin transporter
Synonyms
HTT; 5HTT; OCD1; SERT; 5-HTT; SERT1; hSERT; 5-HTTLPR; Serotonin transporter
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