dsDNase

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: YS0024

Concentration:1 rxn/μl

Size:

Price/Quantity $28

Quantity:

Datasheet

dsDNase

Molecular Biology Products by Assay Biotechnology Inc.

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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408-747-0185

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Product Details

Product Name

dsDNase

Description

dsDNase is a deoxyribonuclease that hydrolyzes phosphodiester bonds in dsDNA, generating oligonucleotides with 5'-phosphate and 3'-hydroxyl ends. dsDNase specifically hydrolyzes dsDNA or the DNA strand in DNA-RNA hybrid chains, while having no effect on RNA and single-stranded DNA. dsDNase is heat-labile and can be rapidly inactivated at 55 ℃ with DTT. It is primarily used to eliminate genomic DNA contamination in RNA samples before reverse transcription. Compared to the traditional method of using DNase I to eliminate genomic DNA contamination, dsDNase does not require additional EDTA, reduces RNA damage, saves experimental time, and ensures accurate quantification of RNA. The activity of dsDNase can be inhibited by EDTA, SDS, DTT, β-mercaptoethanol and high salt concentrations.

Catalog No

YS0024

Application

Properties

No need for additional EDTA inactivation; heat inactivation at 55°C reduces damage to RNA