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Cellular Apoptosis Susceptibility/CSE1L (AB2423) mouse mAb
Cellular Apoptosis Susceptibility/CSE1L (AB2423) mouse mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: W0441
Species Reactivity:Human; Mouse; Rat;
Application:WB; IF; ELISA
Host:Mouse
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$135
Product Details
Product Name
Cellular Apoptosis Susceptibility/CSE1L (AB2423) mouse mAb
Description
Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012],
Catalog No
W0441
Species Reactivity
Human; Mouse; Rat;
Clonality
Monoclonal
Host
Mouse
Modifcation
Unmodified
Clone
AB2423
Isotype
IgG3, kappa
Application
WB; IF; ELISA
Application Dilutions
WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
A synthetic peptide corresponding to the amino acid region 1 - 100 of the human Cellular Apoptosis Susceptibility/CSE1L protein.
Specificity
This antibody detects endogenous levels of CSE1L.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.
Purification
The antibody was purified by protein G affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
CSE1L
Gene ID
1434
Human swiss
P55060
Protein Name
Cellular Apoptosis Susceptibility/CSE1L
Synonyms
CSE1L;CAS;XPO2;Exportin-2;Exp2;Cellular apoptosis susceptibility protein;Chromosome segregation 1-like protein;Importin-alpha re-exporter
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