TGF β Receptor II (AB1599) mouse mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: W0400

Species Reactivity:Human;

Application:IHC; WB; IF; ELISA

Host:Mouse

Clonality:Monoclonal

Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

Size:

Price/Quantity $135

Quantity:

Datasheet

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TGF β Receptor II (AB1599) mouse mAb

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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408-747-0185

Fax

408-747-0145

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Product Details

Product Name

TGF β Receptor II (AB1599) mouse mAb

Description

This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008],

Catalog No

W0400

Species Reactivity

Human;

Clonality

Monoclonal

Host

Mouse

Modifcation

Unmodified

Clone

AB1599

Isotype

IgG1, kappa

Application

IHC; WB; IF; ELISA

Application Dilutions

IHC, 1:100-1:500 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.

Immunogen

A synthetic peptide corresponding to the amino acid region 100 - 200 of the human TGF β Receptor II protein.

Specificity

This antibody detects endogenous levels of TGF β Receptor II protein.

Formulation

The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.

Purification

The antibody was purified by protein G affinity chromatography.

Storage and Stability

Store at-20℃. Avoid freeze / thaw cycles.

Gene Name

TGF-beta receptor type-2 (TGFR-2) (EC 2. 7. 11. 30) (TGF-beta type II receptor) (Transforming growth factor-beta receptor type II) (TGF-beta receptor type II) (TbetaR-II)

Gene ID

7048

Human swiss

P37173

Protein Name

TGF β Receptor II

Synonyms

TGFBR2