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SAF-B Monoclonal Antibody
SAF-B Monoclonal Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: N0743
Reactivity:Human
Applications:WB
Modification:Unmodfied/ Total
Source:Monoclonal Mouse
Storage and Stability:-20°C/1 year

$210
Product Details
Product Name
SAF-B Monoclonal Antibody
Description
scaffold attachment factor B(SAFB) Homo sapiens. This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript v
Catalog No
N0743
Reactivity
Human
Applications
WB
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
Western Blot: 1/1000 - 1/2000. Not yet tested in other applications.
Purification
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
SAFB; HAP; HET; SAFB1; Scaffold attachment factor B1; SAF-B; SAF-B1; HSP27 estrogen response element-TATA box-binding protein; HSP27 ERE-TATA-binding protein
Molecular Weight (Da)
Gene Name
SAFB
Protein Name
Scaffold attachment factor B1
Human Gene ID
6294
Human Swiss Prot No.
Q15424
Immunogen
Purified recombinant human SAF-B protein fragments expressed in E.coli.
Specificity
SAF-B Monoclonal Antibody detects endogenous levels of SAF-B protein.
Formulation
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.
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