Ku70 mouse mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: N0966

Reactivity:Human

Applications:WB,ICC

Modification:Unmodfied/ Total

Source:Monoclonal Mouse

Storage and Stability:-20°C/1 year

Size:

Price/Quantity $160

Quantity:

Datasheet

SDS

Tumor Suppressors/Apoptosis

Ku70 mouse mAb

Western blot detection of Ku70 in Hela.A549.MCF7.Jurkat and Raji cell lysates using Ku70 mouse mAb (1:1000 diluted).Predicted band size:70KDa.Observed band size:70KDa.

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Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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Product Details

Product Name

Ku70 mouse mAb

Description

X-ray repair cross complementing 6(XRCC6)Homo sapiens. The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008],

Catalog No

N0966

Reactivity

Human

Applications

WB,ICC

Modification

Unmodfied/ Total

Source

Monoclonal Mouse

Dilution

wb dilution 1:1000 icc dilution 1:200

Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Storage and Stability

-20°C/1 year

Other Name

5''-deoxyribose-5-phosphate lyase Ku70;5''-dRP lyase Ku70;70 kDa subunit of Ku antigen;ATP dependent DNA helicase 2 subunit 1;ATP dependent DNA helicase II 70 kDa subunit;ATP-dependent DNA helicase 2 subunit 1;ATP-dependent DNA helicase II 70 kDa subunit;CTC box binding factor 75 kDa subunit;CTC box-binding factor 75 kDa subunit;CTC75;CTCBF;CTCBF;DNA repair protein XRCC6;G22P1;Ku 70;Ku autoantigen 70kDa;Ku autoantigen p70 subunit;Ku autoantigen, 70kDa;Ku p70;Ku70;Ku70 DNA binding component of DNA-dependent proteinkinase complex (thyroid autoantigen 70 kDa;Kup70;Lupus Ku autoantigen protein p70;ML8;Thyroid autoantigen 70kD (Ku antigen);Thyroid autoantigen;Thyroid lupus autoantigen;Thyroid lupus autoantigen;Thyroid lupus autoantigen p70;Thyroid-lupus autoantigen;TLAA;TLAA;X ray repair complementing defective repair in Chinese hamster cells 6;X-ray repair complementing defective repair in Chinese hamster cells 6;X-ray repair cross-complementing protein 6;XRCC 6;XRCC6;XRCC6_HUMAN.

Molecular Weight (Da)

Gene Name

xrcc6

Protein Name

Human Gene ID

2547

Human Swiss Prot No.

P12956

Immunogen

Purified recombinant human Ku70 protein fragments expressed in E.coli.

Specificity

This antibody detects endogenous levels of Ku70 and does not cross-react with related proteins.

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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Size:
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Size:
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Publications (1)

Inhibition of Uncoupling Protein 2 Enhances the Radiosensitivity of Cervical Cancer Cells by Promoting the Production of Reactive Oxygen Species

Author: Liu Cui Hua, Huang Zhe Hao, Dong Xin Yu, Zhang Xin Qiang, Li Yuan Hang, Zhao Gang, Sun Bao Sheng, Shen Yan Nan

Date of Publication : 2020-03-04

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Catalog No: N0966

Reactivity:Human

Applications:WB,ICC

Modification:Unmodfied/ Total

Source:Monoclonal Mouse

Storage and Stability:-20°C/1 year

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