tubulin beta 3 class III(TUBB3)Homo sapiens. This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Oct 2010],
Catalog No
N1380
Reactivity
Zebrafish
Applications
WB
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
WB: 1:500-10000
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Zhang. J.. Wong. C.C.. Leung. K.T. et al. FGF18–FGFR2 signaling triggers the activation of c-Jun–YAP1 axis to promote carcinogenesis in a subgroup of gastric cancer patients and indicates translational potential. Oncogene 39. 6647–6663 (2020).
