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Primary Antibodies
Caspase-4 Antibody
Caspase-4 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: R12-2054
Reactivity:Human
Applications:WB,IHC,IF,ELISA
Modification:Unmodified/Total
Source:Polyclonal,Rabbit,IgG
Storage and Stability:Store at -20°C/1 year

$205
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Tumor Suppressors/Apoptosis
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Caspase-4 Antibody

Immunohistochemistry analysis of Caspase-4 antibody in paraffin-embedded human lung carcinoma tissue.

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Product Details
Product Name
Caspase-4 Antibody
Description
This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008],
Catalog No
R12-2054
Reactivity
Human
Source
Polyclonal, Rabbit,IgG
Modification
Unmodified/Total
Applications
WB, IHC, IF, ELISA
Dilution
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
CASP4; ICH2; Caspase-4; CASP-4; ICE(rel)-II; Protease ICH-2; Protease TX
Molecular Weight (Da or kDa)
Gene Name
CASP4
Protein Name
Caspase4
Human Gene ID
837
Human Swiss Prot No.
P49662
Immunogen
The antiserum was produced against synthesized peptide derived from human Caspase-4. AA range:75-124
Specificity
Caspase-4 Polyclonal Antibody detects endogenous levels of Caspase-4 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (1)
Study of the correlation between the noncanonical pathway of pyroptosis and idiopathic inflammatory myopathy. INTERNATIONAL IMMUNOPHARMACOLOGY Int Immunopharmacol. 2021 Sep;98:107810 WB Mouse 1:1000 Skeletal muscle

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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