Claudin 3 is a 22 kDa membrane protein, belonging to the tight junction protein family. It plays the role of tight junction through calcium independent cell adhesion activity. It is expressed in the junction between ductal epithelium and acinar epithelium. There was an increased expression in ovarian cancer, and decreased expression in breast cancer was associated with epithelial mesenchymal transition phenotype.
Catalog No
V0262
Reactivity
Human
Application
IHC
Modification
Unmodified/ Total
Source
Monoclonal Mouse
Storage and Stability
Stable at -20°C for at least 1 year.
Other Name
C7orf1, Claudin-3, Claudin3, CLD3_HUMAN, CLDN 3, Cldn3, Clostridium perfringens enterotoxin receptor 2, CPE R2, CPE receptor 2, CPE-R 2, CPE-receptor 2, CPETR 2, CPETR2, HRVP 1, HRVP1, Rat ventral prostate 1 like protein, Rat ventral prostate.1 protein homolog, RVP1, Ventral prostate.1 like protein, Ventral prostate.1 protein homolog
Gene Name
CLDN3
UniProtKB
O15551
Clone ID
ABT509
Isotype
IgG2b, kappa
Localization
Membranous
Positive Tissue Control
Colon/ Appendix
Specificity
The antibody can specifically recognize human Claudin 3 protein.
