This gene encodes a member of a small family of transcription factors that function through binding of DP interaction partner proteins. The encoded protein recognizes a specific sequence motif in DNA and interacts directly with the retinoblastoma protein (pRB) to regulate the expression of genes involved in the cell cycle. Altered copy number and activity of this gene have been observed in a number of human cancers. There are pseudogenes for this gene on chromosomes 2 and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]
Catalog No
D12061
Reactivity
Human:K168, Mouse:K160, Rat:K161
Applications
WB, ELISA
Modification
Acetyl Specific
Source
Polyclonal Rabbit
Dilution
WB: 1:500-10000 ELISA: 1:10000
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
E2F3 KIAA0075
Molecular Weight (Da)
49162
Gene Name
E2F3 KIAA0075
Protein Name
E2F transcription factor 3
Human Gene ID
1871
Human Swiss Prot No.
O00716
Immunogen
Synthesized acetyl-peptide from human protein at AA range: 130-200
Specificity
The antibody detects endogenous E2F-3 (Acetyl-Lys168) protein
Formulation
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
