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Cytokeratin 8 (Acetyl-Lys483) Antibody
Cytokeratin 8 (Acetyl-Lys483) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: D12135
Reactivity:Human,Rat,Mouse
Applications:WB,IHC,IF,ELISA
Modification:Acetyl Specific
Source:Store at -20°C/1 year
Storage and Stability:

$205
Product Details
Product Name
Cytokeratin 8 (Acetyl-Lys483) Antibody
Description
keratin 8(KRT8) Homo sapiens This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012],
Catalog No
D12135
Reactivity
Human, Rat, Mouse
Source
Polyclonal, Rabbit,IgG
Modification
Acetyl Specific
Applications
WB, IHC, IF, ELISA
Dilution
WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
KRT8; CYK8; Keratin, type II cytoskeletal 8; Cytokeratin-8; CK-8; Keratin-8; K8; Type-II keratin Kb8
Molecular Weight (Da or kDa)
Gene Name
KRT8
Protein Name
Keratin, type II cytoskeletal 8
Human Gene ID
3856
Human Swiss Prot No.
P05787
Immunogen
The antiserum was produced against synthesized Acetyl-peptide derived from human K8 around the Acetylation site of Lys483. AA range:434-483
Specificity
Acetyl-Cytokeratin 8 (K483) Polyclonal Antibody detects endogenous levels of Cytokeratin 8 protein only when acetylated at K483.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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