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Primary Antibodies
Nrf2 (Acetyl-Lys599) Antibody
Nrf2 (Acetyl-Lys599) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: D12157
Reactivity:Human,Mouse,Rat
Applications:WB,IHC-p,IF(paraffin section),ELISA
Modification:Acetyl Specific
Source:Polyclonal Rabbit
Storage and Stability:-20°C/1 year

$205
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Nrf2 (Acetyl-Lys599) Antibody

Western Blot analysis of A549 cells using Acetyl-Nrf2 (K599) Polyclonal Antibody. Antibody was diluted at 1:1000. Secondary antibody(catalogNo.:SA0002) was diluted at 1:20000

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Product Details
Product Name
Nrf2 (Acetyl-Lys599) Antibody
Description
This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene. [provided by RefSeq, Sep 2015]
Catalog No
D12157
Reactivity
Human, Mouse, Rat
Applications
WB, IHC-p, IF(paraffin section), ELISA
Modification
Acetyl Specific
Source
Polyclonal Rabbit
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/10000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
NFE2L2; NRF2; Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor, erythroid derived 2, like 2
Molecular Weight (Da)
75-100
Gene Name
NFE2L2
Protein Name
Nuclear factor erythroid 2-related factor 2
Human Gene ID
4780
Human Swiss Prot No.
Q16236
Immunogen
Synthesized acetyl-peptide derived from the C-terminal region of human Nrf2 around the acetylation site of K599.
Specificity
Acetyl-Nrf2 (K599) Polyclonal Antibody detects endogenous levels of Nrf2 protein only when acetylation at K599.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (2)
The link between deacetylation and hepatotoxicity induced by exposure to hexavalent chromium

Author: Qingyue Yang, Bing Han, Siyu Li, Xiaoqiao Wang, Pengfei Wu, Yan Liu, Jiayi Li, Biqi Han, Ning Deng, Zhigang Zhang

Date of Publication : 2021-04-08

Histone deacetylase inhibition activates Nrf2 and protects against osteoarthritis

Author: Cai, Dawei, Yin, Shasha, Yang, Jun, Jiang, Qing, Cao, Wangsen

Date of Publication : 2015-09-26

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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