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Primary Antibodies
p53 (Acetyl-K120) Antibody
p53 (Acetyl-K120) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: D12167
Reactivity:Human:K120,Mouse:K114,Rat:K118
Applications:WB,ELISA
Modification:Acetyl Specific
Source:Store at -20°C/1 year
Storage and Stability:

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p53 (Acetyl-K120) Antibody

Western Blot analysis of 1,mouse-liver 2,hela 3,mouse-brain cells using primary antibody diluted at 1:1000(4°C overnight). Secondary antibody:Goat Anti-rabbit IgG IRDye 800( diluted at 1:5000, 25°C, 1 hour)

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Product Details
Product Name
p53 (Acetyl-K120) Antibody
Description
tumor protein p53(TP53) Homo sapiens This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013],
Catalog No
D12167
Reactivity
Human:K120, Mouse:K114, Rat:K118
Source
Polyclonal, Rabbit,IgG
Modification
Acetyl Specific
Applications
WB, ELISA
Dilution
WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Molecular Weight (Da or kDa)
44kD
Gene Name
TP53 P53
Protein Name
p53
Human Gene ID
7157
Human Swiss Prot No.
P04637
Immunogen
Synthesized Acetyl peptide derived from human p53. at AA range: K120
Specificity
This antibody detects endogenous levels of p53 at Human:K120;Mouse:K114;Rat:K118, It doesn't reacte with total protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (1)
RNF8 promotes efficient DSB repair by inhibiting the pro‐apoptotic activity of p53 through regulating the function of Tip60. CELL PROLIFERATION Cell Proliferat. 2020 Mar;53(3):e12780 WB Human HCT116 cell,HEK-293T cell

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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