Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015]
Catalog No
D12225
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA
Modification
Acetyl Specific
Source
Polyclonal Rabbit
Dilution
WB 1:1000-2000 ELISA 1:5000-20000
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
Histone H1.1 (Histone H1a)
Molecular Weight (Da)
23650
Gene Name
HIST1H1A H1F1
Protein Name
Histone H1 (Acetyl Lys66/63/64)
Human Gene ID
3024
Human Swiss Prot No.
Q02539/P16403/P16402/P10412
Immunogen
Synthesized peptide derived from human Histone H1 (Acetyl Lys66/63/64)
Specificity
This antibody detects endogenous levels of Human,Mouse,Rat Histone H1 (Acetyl Lys66/63/64)
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
