Cleaved-Aggrecan (D369) Antibody (L0101)

Cleaved-Aggrecan (D369) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: L0101

Reactivity:Human,Rat

Applications:WB,IHC-p,IF(paraffin section),ELISA

Modification:Cleaved Specific

Source:Polyclonal Rabbit

Storage and Stability:-20°C/1 year

Size:

Price/Quantity $205

Quantity:

Datasheet

SDS

Neurobiology

Cleaved-Aggrecan (D369) Antibody

Western blot analysis of lysates from Jurkat cells, treated with Etoposide 25uM 60', using Aggrecan (Cleaved-Asp369) Antibody. The lane on the right is blocked with the synthesized peptide.

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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Product Details

Product Name

Cleaved-Aggrecan (D369) Antibody

Description

This gene is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the Extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene. [provided by RefSeq, Jul 2008]

Catalog No

L0101

Reactivity

Human, Rat

Applications

WB, IHC-p, IF(paraffin section), ELISA

Modification

Cleaved Specific

Source

Polyclonal Rabbit

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Storage and Stability

-20°C/1 year

Other Name

ACAN; AGC1; CSPG1; MSK16; Aggrecan core protein; Cartilage-specific proteoglycan core protein; CSPCP; Chondroitin sulfate proteoglycan core protein 1; Chondroitin sulfate proteoglycan 1

Molecular Weight (Da)

250193

Gene Name

ACAN

Protein Name

Aggrecan core protein

Human Gene ID

176

Human Swiss Prot No.

P16112

Immunogen

The antiserum was produced against synthesized peptide derived from human Aggrecan. AA range:320-369

Specificity

Cleaved-Aggrecan (D369) Polyclonal Antibody detects endogenous levels of fragment of activated Aggrecan protein resulting from cleavage adjacent to D369.

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.