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Cleaved-Caspase-6 p18 (D179) Antibody

Catalog No : L0106
  • Reactivity
    Human,Rat
  • Applications
    WB,IHC-p,IF(paraffin section),ELISA
  • Modification
    Cleaved Specific
  • Source
    Polyclonal Rabbit
  • Storage and Stability
    -20°C/1 year
  • Size
    50 μl
  • Price/Quantity
    $205
  • Quantity
Details
  • Product Name
    Cleaved-Caspase-6 p18 (D179) Antibody
  • Description
    This gene encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Oct 2015]
  • Catalog No
    L0106
  • Reactivity
    Human, Rat
  • Applications
    WB, IHC-p, IF(paraffin section), ELISA
  • Modification
    Cleaved Specific
  • Source
    Polyclonal Rabbit
  • Dilution
    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
  • Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration
    1 mg/ml
  • Storage and Stability
    -20°C/1 year
  • Other Name
    CASP6; MCH2; Caspase-6; CASP-6; Apoptotic protease Mch-2
  • Molecular Weight (Da)
    33310
  • Gene Name
    CASP6
  • Protein Name
    Caspase6
  • Human Gene ID
    839
  • Human Swiss Prot No.
    P55212
  • Immunogen
    The antiserum was produced against synthesized peptide derived from human Caspase 6. AA range:130-179
  • Specificity
    Cleaved-Caspase-6 p18 (D179) Polyclonal Antibody detects endogenous levels of fragment of activated Caspase-6 p18 protein resulting from cleavage adjacent to D179.
  • Formulation
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.