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Primary Antibodies
Cleaved-Caspase-7 (S199) Antibody
Cleaved-Caspase-7 (S199) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: L0109
Reactivity:Human,Mouse
Applications:WB,IHC,IF,ELISA
Modification:Cleaved Specific
Source:Store at -20°C/1 year
Storage and Stability:

$205
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Tumor Suppressors/Apoptosis
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Cleaved-Caspase-7 (S199) Antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Caspase 7 (Cleaved-Asp198) Antibody. The picture on the right is blocked with the synthesized peptide.

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Product Details
Product Name
Cleaved-Caspase-7 (S199) Antibody
Description
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012],
Catalog No
L0109
Reactivity
Human, Mouse
Source
Polyclonal, Rabbit,IgG
Modification
Cleaved Specific
Applications
WB, IHC, IF, ELISA
Dilution
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
CASP7; MCH3; Caspase-7; CASP-7; Apoptotic protease Mch-3; CMH-1; ICE-like apoptotic protease 3; ICE-LAP3
Molecular Weight (Da or kDa)
Gene Name
CASP7
Protein Name
Caspase7
Human Gene ID
840
Human Swiss Prot No.
P55210
Immunogen
The antiserum was produced against synthesized peptide derived from human Caspase 7. AA range:180-229
Specificity
Cleaved-Caspase-7 (S199) Polyclonal Antibody detects endogenous levels of fragment of activated Caspase-7 protein resulting from cleavage adjacent to S199.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (2)
Terbinafine prevents colorectal cancer growth by inducing dNTP starvation and reducing immune suppression WB Human 1:1000 /HCT116, HT-29 cells

Author: Available in link provided

Date of Publication : Available in link provided

Combination of ruxolitinib with ABT-737 exhibits synergistic effects in cells carrying concurrent JAK2V617F and ASXL1 mutations INVESTIGATIONAL NEW DRUGS Jing Yang WB Human

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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