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Primary Antibodies
Cleaved-Cathepsin D HC (L169) Antibody
Cleaved-Cathepsin D HC (L169) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: L0176
Reactivity:Human,Rat,Mouse
Applications:WB,ELISA
Modification:Cleaved Specific
Source:Store at -20°C/1 year
Storage and Stability:

$205
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Cleaved-Cathepsin D HC (L169) Antibody

Western blot analysis of lysates from 293, A549, and JurKat cells, treated with etoposide 25uM 1h, using CATD (heavy chain,Cleaved-Leu169) Antibody. The lane on the right is blocked with the synthesized peptide.

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Product Details
Product Name
Cleaved-Cathepsin D HC (L169) Antibody
Description
This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015],
Catalog No
L0176
Reactivity
Human, Rat, Mouse
Source
Polyclonal, Rabbit,IgG
Modification
Cleaved Specific
Applications
WB, ELISA
Dilution
WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
CTSD; CPSD; Cathepsin D
Molecular Weight (Da or kDa)
Gene Name
CTSD
Protein Name
Cathepsin D
Human Gene ID
1509
Human Swiss Prot No.
P07339
Immunogen
The antiserum was produced against synthesized peptide derived from human CATD. AA range:150-199
Specificity
Cleaved-Cathepsin D HC (L169) Polyclonal Antibody detects endogenous levels of fragment of activated Cathepsin D HC protein resulting from cleavage adjacent to L169.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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