Cleaved-Factor X/ Factor X LC (A41) Antibody (L0199)

Cleaved-Factor X/ Factor X LC (A41) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: L0199

Reactivity:Human,Rat,Mouse

Applications:WB,ELISA

Modification:Cleaved Specific

Source:Store at -20°C/1 year

Storage and Stability:

Size:

Price/Quantity $205

Quantity:

Datasheet

SDS

Signaling Intermediates

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Cleaved-Factor X/ Factor X LC (A41) Antibody

Western Blot analysis of various cells using Cleaved-Factor X/ Factor X LC (A41) Polyclonal Antibody

Delivery

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

Telephone

408-747-0185

Fax

408-747-0145

order@assaybiotech.com

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Product Details

Product Name

Cleaved-Factor X/ Factor X LC (A41) Antibody

Description

This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity. Alternative sp

Catalog No

L0199

Reactivity

Human, Rat, Mouse

Source

Polyclonal, Rabbit,IgG

Modification

Cleaved Specific

Applications

WB, ELISA

Dilution

WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Storage and Stability

Store at -20°C/1 year

Other Name

F10; Coagulation factor X; Stuart factor; Stuart-Prower factor

Molecular Weight (Da or kDa)

Gene Name

F10

Protein Name

Coagulation factor X

Human Gene ID

2159

Human Swiss Prot No.

P00742

Immunogen

The antiserum was produced against synthesized peptide derived from human FA10. AA range:22-71

Specificity

Cleaved-Factor X/ Factor X LC (A41) Polyclonal Antibody detects endogenous levels of fragment of activated Factor X/ Factor X LC protein resulting from cleavage adjacent to A41.

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.