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Primary Antibodies
Cleaved-Factor XIIIa (G39) Antibody
Cleaved-Factor XIIIa (G39) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: L0206
Reactivity:Human,Rat,Mouse
Applications:WB,ELISA
Modification:Cleaved Specific
Source:Store at -20°C/1 year
Storage and Stability:

$205
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Cleaved-Factor XIIIa (G39) Antibody

Western blot analysis of lysates from Jurkat cells, treated with etoposide 25uM 24h, using FA13A (Cleaved-Gly39) Antibody. The lane on the right is blocked with the synthesized peptide.

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Product Details
Product Name
Cleaved-Factor XIIIa (G39) Antibody
Description
This gene encodes the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. It also crosslinks alpha-2-plasmin inhibitor, or
Catalog No
L0206
Reactivity
Human, Rat, Mouse
Source
Polyclonal, Rabbit,IgG
Modification
Cleaved Specific
Applications
WB, ELISA
Dilution
WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
F13A1; F13A; Coagulation factor XIII A chain; Coagulation factor XIIIa; Protein-glutamine gamma-glutamyltransferase A chain; Transglutaminase A chain
Molecular Weight (Da or kDa)
Gene Name
F13A1
Protein Name
Coagulation factor XIII A chain
Human Gene ID
2162
Human Swiss Prot No.
P00488
Immunogen
The antiserum was produced against synthesized peptide derived from human FA13A. AA range:20-69
Specificity
Cleaved-Factor XIIIa (G39) Polyclonal Antibody detects endogenous levels of fragment of activated Factor XIIIa protein resulting from cleavage adjacent to G39.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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