Cleaved-Plasminogen HC A short form (V98) Antibody
Description
The protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009]
Catalog No
L0370
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA
Modification
Cleaved Specific
Source
Polyclonal Rabbit
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
PLG; Plasminogen
Molecular Weight (Da)
90569
Gene Name
PLG
Protein Name
Plasminogen
Human Gene ID
5340
Human Swiss Prot No.
P00747
Immunogen
The antiserum was produced against synthesized peptide derived from human PLMN. AA range:79-128
Specificity
Cleaved-Plasminogen HC A short form (V98) Polyclonal Antibody detects endogenous levels of fragment of activated Plasminogen HC A short form protein resulting from cleavage adjacent to V98.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Western blot analysis of PLMN (heavy chain A short form, Cleaved-Val98) Antibody. The lane on the right is blocked with the PLMN (heavy chain A short form, Cleaved-Val98) peptide.
