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Collagen V α1 (Cleaved-Ala1605) Antibody
Collagen V α1 (Cleaved-Ala1605) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: L0386
Reactivity:Human,Rat,Mouse
Applications:WB,ELISA
Modification:Cleaved Specific
Source:Store at -20°C/1 year
Storage and Stability:

$205
Product Details
Product Name
Collagen V α1 (Cleaved-Ala1605) Antibody
Description
disease:Defects in COL5A1 are a cause of Ehlers-Danlos syndrome type 1 (EDS1) [MIM:130000]; also known as Ehlers-Danlos syndrome gravis or severe classic type Ehlers-Danlos syndrome. EDS is a connective tissue disorder characterized by hyperextensible skin, atrophic cutaneous scars due to tissue fragility and joint hyperlaxity. EDS1 is the severe form of classic Ehlers-Danlos syndrome.,disease:Defects in COL5A1 are a cause of Ehlers-Danlos syndrome type 2 (EDS2) [MIM:130010]; also known as Ehlers-Danlos syndrome mitis or mild classic type Ehlers Danlos syndrome.,function:Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin.,PTM:Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.,PTM:Sulfated on 40% of tyrosines.,similarity:Belongs to the fibrillar collagen family.,similarity:Contains 1 laminin G-like domain.,similarity:Contains 1 TSP N-terminal (TSPN) domain.,subunit:Trimers of two alpha 1(V) and one alpha 2(V) chains in most tissues and trimers of one alpha 1(V), one alpha 2(V), and one alpha 3(V) chains in placenta. Interacts with CSPG4.,
Catalog No
L0386
Reactivity
Human, Rat, Mouse
Source
Polyclonal, Rabbit,IgG
Modification
Cleaved Specific
Applications
WB, ELISA
Dilution
WB 1:1000-2000 ELISA 1:5000-20000
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
Collagen alpha-1(V) chain
Molecular Weight (Da or kDa)
Gene Name
COL5A1
Protein Name
Collagen V α1 (Cleaved-Ala1605)
Human Gene ID
1289
Human Swiss Prot No.
P20908
Immunogen
Synthesized peptide derived from human Collagen V α1 (Cleaved-Ala1605)
Specificity
This antibody detects endogenous levels of Human Collagen V α1 (Cleaved-Ala1605, protein was cleaved amino acid sequence between 1605-1606 )
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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