This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. Mutations in this gene are associated with Ehlers-Danlos syndrome, types I and II. [provided by RefSeq, Jul 2008]
Catalog No
L0387
Reactivity
Human, Rat, Mouse
Applications
WB, ELISA
Modification
Cleaved Specific
Source
Polyclonal Rabbit
Dilution
WB 1:1000-2000 ELISA 1:5000-20000
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
Collagen alpha-2(V) chain
Molecular Weight (Da)
164890
Gene Name
COL5A2
Protein Name
Collagen V α2 (Cleaved-Leu1229)
Human Gene ID
1290
Human Swiss Prot No.
P05997
Immunogen
Synthesized peptide derived from human Collagen V α2 (Cleaved-Leu1229)
Specificity
This antibody detects endogenous levels of Human Collagen V α2 (Cleaved-Leu1229, protein was cleaved amino acid sequence between 1229-1230 )
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
