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Primary Antibodies
MMP8 (Cleaved-Leu101) Antibody
MMP8 (Cleaved-Leu101) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: L0468
Reactivity:Human,Mouse,Rat
Applications:WB,IHC
Modification:Cleaved Specific
Source:Store at -20°C/1 year
Storage and Stability:

$205
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MMP8 (Cleaved-Leu101) Antibody

Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).

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Product Details
Product Name
MMP8 (Cleaved-Leu101) Antibody
Description
catalytic activity:Cleavage of interstitial collagens in the triple helical domain. Unlike EC 3.4.24.7, this enzyme cleaves type III collagen more slowly than type I.,cofactor:Binds 2 zinc ions per subunit.,cofactor:Binds 3 calcium ions per subunit.,domain:The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.,enzyme regulation:Cannot be activated without removal of the activation peptide.,function:Can degrade fibrillar type I, II, and III collagens.,similarity:Belongs to the peptidase M10A family.,similarity:Contains 4 hemopexin-like domains.,subcellular location:Stored in intracellular granules.,tissue specificity:Neutrophils.,
Catalog No
L0468
Reactivity
Human, Mouse, Rat
Source
Polyclonal, Rabbit,IgG
Modification
Cleaved Specific
Applications
WB, IHC
Dilution
WB 1:500-2000;IHC 1:50-300
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
Neutrophil collagenase (EC 3.4.24.34; Matrix metalloproteinase-8; MMP-8; PMNL collagenase; PMNL-CL)
Molecular Weight (Da or kDa)
Gene Name
MMP8 CLG1
Protein Name
MMP8 (Cleaved-Leu101)
Human Gene ID
4317
Human Swiss Prot No.
P22894
Immunogen
Synthesized peptide derived from human MMP8 (Cleaved-Leu101)
Specificity
This antibody detects endogenous levels of Human,Mouse,Rat MMP8 (Cleaved-Leu101, protein was cleaved amino acid sequence between 100-101 )
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Primary Antibodies

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    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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