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Primary Antibodies
Caspase 4 (p10, Cleaved-Ala290) Antibody
Caspase 4 (p10, Cleaved-Ala290) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: L0480
Reactivity:Human
Applications:WB,ELISA
Modification:Cleaved Specific
Source:Store at -20°C/1 year
Storage and Stability:

$205
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Tumor Suppressors/Apoptosis
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Caspase 4 (p10, Cleaved-Ala290) Antibody

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Product Details
Product Name
Caspase 4 (p10, Cleaved-Ala290) Antibody
Description
catalytic activity:Strict requirement for Asp at the P1 position. It has a preferred cleavage sequence of Tyr-Val-Ala-Asp-|- but also cleaves at Asp-Glu-Val-Asp-|-.,function:Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves caspase-1.,PTM:The two subunits are derived from the precursor sequence by an autocatalytic mechanism or by cleavage by Caspase-8.,similarity:Belongs to the peptidase C14A family.,similarity:Contains 1 CARD domain.,subunit:Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a small and a large subunit.,tissue specificity:Widely expressed, with highest levels in spleen and lung. Moderate expression in heart and liver, low expression in skeletal muscle, kidney and testis. Not found in the brain.,
Catalog No
L0480
Reactivity
Human
Source
Polyclonal, Rabbit,IgG
Modification
Cleaved Specific
Applications
WB, ELISA
Dilution
WB 1:1000-2000 ELISA 1:5000-20000
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
Caspase-4 (CASP-4; EC 3.4.22.57; ICE(rel)-II; Protease ICH-2; Protease TX) [Cleaved into: Caspase-4 subunit 1; Caspase-4 subunit 2]
Molecular Weight (Da or kDa)
Gene Name
CASP4 ICH2
Protein Name
Caspase4
Human Gene ID
837
Human Swiss Prot No.
P49662
Immunogen
Synthesized peptide derived from human Caspase 4 (p10, Cleaved-Ala290)
Specificity
This antibody detects endogenous levels of Human Caspase 4 (p10, Cleaved-Ala290, protein was cleaved amino acid sequence between 289-290)
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (1)
Antitumor Effect of Fluoxetine on Chronic Stress-Promoted Lung Cancer Growth via Suppressing Kynurenine Pathway and Enhancing Cellular Immunity. Frontiers in Pharmacology Front Pharmacol. 2021 Aug;0:1609 WB Mouse 1:2000 A549 cell-xenograft

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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