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Primary Antibodies
FAK (Phospho-Tyr576) Antibody
FAK (Phospho-Tyr576) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A0426
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,IF,ELISA
Modification:Phospho Specific
Source:Store at -20°C/1 year
Storage and Stability:

$205
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FAK (Phospho-Tyr576) Antibody

Immunohistochemistry analysis of paraffin-embedded human brain, using FAK (Phospho-Tyr576) Antibody. The picture on the right is blocked with the phospho peptide.

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Product Details
Product Name
FAK (Phospho-Tyr576) Antibody
Description
protein tyrosine kinase 2(PTK2) Homo sapiens This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only four of them have been determined. [provided by RefSeq, Oct 2015],
Catalog No
A0426
Reactivity
Human, Mouse, Rat
Source
Polyclonal, Rabbit,IgG
Modification
Phospho Specific
Applications
WB, IHC, IF, ELISA
Dilution
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
PTK2; FAK; FAK1; Focal adhesion kinase 1; FADK 1; Focal adhesion kinase-related nonkinase; FRNK; Protein phosphatase 1 regulatory subunit 71; PPP1R71; Protein-tyrosine kinase 2; p125FAK; pp125FAK
Molecular Weight (Da or kDa)
Gene Name
PTK2
Protein Name
Focal adhesion kinase 1
Human Gene ID
5747
Human Swiss Prot No.
Q05397
Immunogen
The antiserum was produced against synthesized peptide derived from human FAK around the phosphorylation site of Tyr576. AA range:542-591
Specificity
Phospho-FAK (Y576) Polyclonal Antibody detects endogenous levels of FAK protein only when phosphorylated at Y576.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (3)
Albumin Fusion at the N-Terminus or C-Terminus of HM-3 Leads to Improved Pharmacokinetics and Bioactivities. Biomedicines Biomedicines. 2021 Sep;9(9):1084 WB Mouse Murine melanoma cells (B16F10)

Author: Available in link provided

Date of Publication : Available in link provided

HM-3-HSA exhibits potent anti-angiogenesis and antitumor activity in hepatocellular carcinoma. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES Eur J Pharm Sci. 2021 Sep;:106017 WB Human HUVECs

Author: Available in link provided

Date of Publication : Available in link provided

Lu, Jian, et al. "Role of LKB1 in migration and invasion of Cr (VI)-transformed human bronchial epithelial Beas-2B cells." Anti-cancer drugs 29.7 (2018): 660-673.

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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