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FANCD2 (Phospho-Ser222) Antibody
FANCD2 (Phospho-Ser222) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A0427
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,IF,ELISA
Modification:Phospho Specific
Source:Store at -20°C/1 year
Storage and Stability:

$205
Product Details
Product Name
FANCD2 (Phospho-Ser222) Antibody
Description
Fanconi anemia complementation group D2(FANCD2) Homo sapiens The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex.This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repai
Catalog No
A0427
Reactivity
Human, Mouse, Rat
Source
Polyclonal, Rabbit,IgG
Modification
Phospho Specific
Applications
WB, IHC, IF, ELISA
Dilution
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
FANCD2; FACD; Fanconi anemia group D2 protein; Protein FACD2
Molecular Weight (Da or kDa)
Gene Name
FANCD2
Protein Name
Fanconi anemia group D2 protein
Human Gene ID
2177
Human Swiss Prot No.
Q9BXW9
Immunogen
The antiserum was produced against synthesized peptide derived from human FANCD2 around the phosphorylation site of Ser222. AA range:188-237
Specificity
Phospho-FANCD2 (S222) Polyclonal Antibody detects endogenous levels of FANCD2 protein only when phosphorylated at S222.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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