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JAK2 (Phospho-Tyr570) Antibody
JAK2 (Phospho-Tyr570) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A0499
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,IF,ELISA
Modification:Phospho Specific
Source:Store at -20°C/1 year
Storage and Stability:

$205
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JAK2 (Phospho-Tyr570) Antibody

Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using JAK2 (Phospho-Tyr570) Antibody

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Product Details
Product Name
JAK2 (Phospho-Tyr570) Antibody
Description
This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. [provided by RefSeq, Jul 2008],
Catalog No
A0499
Reactivity
Human, Mouse, Rat
Source
Polyclonal, Rabbit,IgG
Modification
Phospho Specific
Applications
WB, IHC, IF, ELISA
Dilution
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
JAK2; Tyrosine-protein kinase JAK2; Janus kinase 2; JAK-2
Molecular Weight (Da or kDa)
Gene Name
JAK2
Protein Name
Tyrosine-protein kinase JAK2
Human Gene ID
3717
Human Swiss Prot No.
O60674
Immunogen
The antiserum was produced against synthesized peptide derived from human JAK2 around the phosphorylation site of Tyr570. AA range:541-590
Specificity
Phospho-JAK2 (Y570) Polyclonal Antibody detects endogenous levels of JAK2 protein only when phosphorylated at Y570.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (7)
Glycogen metabolism regulates macrophage-mediated acute inflammatory responses. Nature Communications Nat Commun. 2020 Apr;11(1):1-16 WB Mouse 1:1000 BMDMs

Author: Available in link provided

Date of Publication : Available in link provided

Effects and Molecular Mechanism of Single-Nucleotide Polymorphisms of MEG3 on Porcine Skeletal Muscle Development. Frontiers in Genetics Front Genet. 2021 Feb;12:206 WB Porcine 1 : 1000 Porcine skeletal muscle satellite cells

Author: Available in link provided

Date of Publication : Available in link provided

miRNA-331-3p Affects the Proliferation, Metastasis, and Invasion of Osteosarcoma through SOCS1/JAK2/STAT3 Journal of Oncology Bing Wu WB Mouse

Author: Available in link provided

Date of Publication : Available in link provided

Progranulin promoted the proliferation, metastasis, and suppressed apoptosis via JAK2-STAT3/4 signaling pathway in papillary thyroid carcinoma. Cancer Cell International Zhen Liu WB Human 1:800 BCPAP cell,TPC1 cell

Author: Available in link provided

Date of Publication : Available in link provided

Shenlian extract improves atherosclerosis by relieving adventitial inflammation. JOURNAL OF ETHNOPHARMACOLOGY Xiaoxin Zhu WB Rat vascular adventitial fibroblasts (VAFs)

Author: Available in link provided

Date of Publication : Available in link provided

Overexpression of miR-506-3p reversed doxorubicin resistance in drug-resistant osteosarcoma cells Frontiers in Pharmacology Wang Xinru WB Human 1:1000 U-2OS/Dox cell

Author: Available in link provided

Date of Publication : Available in link provided

PCV2 Induced Endothelial Derived IL-8 Affects MoDCs Maturation Mainly via NF-κB Signaling Pathway Viruses-Basel Mengyu Zhang WB Pig monocyte-derived dendritic cell (MoDC),porcine hip artery endothelial cell (PIEC)

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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