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Primary Antibodies
p70 S6 kinase α (Phospho-Ser418) Antibody
p70 S6 kinase α (Phospho-Ser418) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A0534
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,IF,ELISA
Modification:Phospho Specific
Source:Store at -20°C/1 year
Storage and Stability:

$205
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p70 S6 kinase α (Phospho-Ser418) Antibody

Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using p70 S6 Kinase (Phospho-Ser418) Antibody

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Product Details
Product Name
p70 S6 kinase α (Phospho-Ser418) Antibody
Description
ribosomal protein S6 kinase B1(RPS6KB1) Homo sapiens This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013],
Catalog No
A0534
Reactivity
Human, Mouse, Rat
Source
Polyclonal, Rabbit,IgG
Modification
Phospho Specific
Applications
WB, IHC, IF, ELISA
Dilution
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
RPS6KB1; STK14A; Ribosomal protein S6 kinase beta-1; S6K-beta-1; S6K1; 70 kDa ribosomal protein S6 kinase 1; P70S6K1; p70-S6K 1; Ribosomal protein S6 kinase I; Serine/threonine-protein kinase 14A; p70 ribosomal S6 kinase alpha; p70 S6 kinas
Molecular Weight (Da or kDa)
Gene Name
RPS6KB1 STK14A P70S6K
Protein Name
Ribosomal protein S6 kinase beta-1
Human Gene ID
6198
Human Swiss Prot No.
P23443
Immunogen
The antiserum was produced against synthesized peptide derived from human p70 S6 Kinase around the phosphorylation site of Ser418. AA range:384-433
Specificity
Phospho-p70 S6 kinase α (S418) Polyclonal Antibody detects endogenous levels of p70 S6 kinase α protein only when phosphorylated at S418.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (5)
Notum produced by Paneth cells attenuates regeneration of aged intestinal epithelium. NATURE 2019 Jul 10 WB Mouse 1:500 crypts tissue Paneth cell

Author: Available in link provided

Date of Publication : Available in link provided

Mammalian elongation factor 4 regulates mitochondrial translation essential for spermatogenesis. NATURE STRUCTURAL & MOLECULAR BIOLOGY 2016 Apr 11 WB Mouse heart

Author: Available in link provided

Date of Publication : Available in link provided

Berberine induces miR-373 expression in hepatocytes to inactivate hepatic steatosis associated AKT-S6 kinase pathway. EUROPEAN JOURNAL OF PHARMACOLOGY Eur J Pharmacol. 2018 Apr;825:107 WB Human MIHA cell, HepG2 cell

Author: Available in link provided

Date of Publication : Available in link provided

Fluoride regulates chondrocyte proliferation and autophagy via PI3K/AKT/mTOR signaling pathway. CHEMICO-BIOLOGICAL INTERACTIONS Chem-Biol Interact. 2021 Nov;349:109659 WB Mouse 1:1000 ATDC5 cells

Author: Available in link provided

Date of Publication : Available in link provided

Inhibitor PF-04691502 works as a senolytic to regulate cellular senescence EXPERIMENTAL GERONTOLOGY Ziqiang Fan WB Mouse 1:500 NIH-3T3 cell

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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