Crystallin-αB (Phospho-Ser59) Antibody (A0897)

Crystallin-αB (Phospho-Ser59) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A0897

Reactivity:Human,Mouse,Rat

Applications:IHC,IF,ELISA

Modification:Phospho Specific

Source:Store at -20°C/1 year

Storage and Stability:

Size:

Price/Quantity $205

Quantity:

Datasheet

SDS

Signaling Intermediates

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Crystallin-αB (Phospho-Ser59) Antibody

Immunohistochemistry analysis of paraffin-embedded human skeletal muscle, using CRYAB/Crystallin-alpha-B (Phospho-Ser59) Antibody. The picture on the right is blocked with the phospho peptide.

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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408-747-0145

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Product Details

Product Name

Crystallin-αB (Phospho-Ser59) Antibody

Description

Mammalian lens crystallins are divided into alpha, beta, and gamma families. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone; instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. These heterogeneous aggregates consist of 30-40 subunits; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distin

Catalog No

A0897

Reactivity

Human, Mouse, Rat

Source

Polyclonal, Rabbit,IgG

Modification

Phospho Specific

Applications

IHC, IF, ELISA

Dilution

IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Storage and Stability

Store at -20°C/1 year

Other Name

CRYAB; CRYA2; Alpha-crystallin B chain; Alpha(B)-crystallin; Heat shock protein beta-5; HspB5; Renal carcinoma antigen NY-REN-27; Rosenthal fiber component

Molecular Weight (Da or kDa)

20kD

Gene Name

CRYAB

Protein Name

Alpha-crystallin B chain

Human Gene ID

1410

Human Swiss Prot No.

P02511

Immunogen

The antiserum was produced against synthesized peptide derived from human CRYAB/Crystallin-alpha-B around the phosphorylation site of Ser59. AA range:31-80

Specificity

Phospho-Crystallin-αB (S59) Polyclonal Antibody detects endogenous levels of Crystallin-αB protein only when phosphorylated at S59.

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.