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Primary Antibodies
JAK3 (Phospho-Tyr785) Antibody
JAK3 (Phospho-Tyr785) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A1080
Reactivity:Human,Mouse,Rat
Applications:WB,IHC-p,IF(paraffin section),ELISA
Modification:Phospho Specific
Source:Polyclonal Rabbit
Storage and Stability:-20°C/1 year

$205
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JAK3 (Phospho-Tyr785) Antibody

Western Blot analysis of 453 cells using Phospho-JAK3 (Y785) Polyclonal Antibody diluted at 1:1000

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Product Details
Product Name
JAK3 (Phospho-Tyr785) Antibody
Description
The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008]
Catalog No
A1080
Reactivity
Human, Mouse, Rat
Applications
WB, IHC-p, IF(paraffin section), ELISA
Modification
Phospho Specific
Source
Polyclonal Rabbit
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
JAK3; Tyrosine-protein kinase JAK3; Janus kinase 3; JAK-3; Leukocyte janus kinase; L-JAK
Molecular Weight (Da)
125099
Gene Name
JAK3
Protein Name
Tyrosine-protein kinase JAK3
Human Gene ID
3718
Human Swiss Prot No.
P52333
Immunogen
The antiserum was produced against synthesized peptide derived from human JAK3 around the phosphorylation site of Tyr785. AA range:751-800
Specificity
Phospho-JAK3 (Y785) Polyclonal Antibody detects endogenous levels of JAK3 protein only when phosphorylated at Y785.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (1)
Paeoniflorin‐6′‐o‐benzene sulfonate (CP‐25) improves vasculitis through inhibiting IL‐17A/JAK/STAT3 signaling pathway in endothelial cells of HFD CIA rats

Author: Xiao-Yu Cai, Jing-Ru Ge, Li Xu, Fa-Qin Liang, Yue Zhu, Yu Tai, Xian-Zheng Zhang, Jin-Ling Shu, Dan Mei, Le Han, Chen Wang, Xiao-Yu Tang, Ling-Ling Zhang, Wei Wei

Date of Publication : 2020-10-02

Primary Antibodies

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    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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