KCNQ2/3/4/5 (Phospho-Thr217/246/223/251) Antibody (A1089)

KCNQ2/3/4/5 (Phospho-Thr217/246/223/251) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A1089

Reactivity:Human,Mouse,Rat

Applications:WB,IHC,IF,ELISA

Modification:Phospho Specific

Source:Store at -20°C/1 year

Storage and Stability:

Size:

Price/Quantity $205

Quantity:

Datasheet

SDS

Channel Proteins

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KCNQ2/3/4/5 (Phospho-Thr217/246/223/251) Antibody

Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using Kv7.3/KCNQ3 (Phospho-Thr246) Antibody

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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408-747-0185

Fax

408-747-0145

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Product Details

Product Name

KCNQ2/3/4/5 (Phospho-Thr217/246/223/251) Antibody

Description

The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association ofThe protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Catalog No

A1089

Reactivity

Human, Mouse, Rat

Source

Polyclonal, Rabbit,IgG

Modification

Phospho Specific

Applications

WB, IHC, IF, ELISA

Dilution

WB 1:500-2000 IHC 1:100 - 1:300. ELISA: 1:20000. IF 1:50-200

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Storage and Stability

Store at -20°C/1 year

Other Name

KCNQ2; Potassium voltage-gated channel subfamily KQT member 2; KQT-like 2; Neuroblastoma-specific potassium channel subunit alpha KvLQT2; Voltage-gated potassium channel subunit Kv7.2; KCNQ3; Potassium voltage-gated channel subfamily KQT me

Molecular Weight (Da or kDa)

97kD

Gene Name

KCNQ2

Protein Name

Potassium voltage-gated channel subfamily KQT member 2

Human Gene ID

3785/3786/9132/56479

Human Swiss Prot No.

O43526 / O43525 / P56696 / Q9NR82

Immunogen

The antiserum was produced against synthesized peptide derived from human Kv7.3/KCNQ3 around the phosphorylation site of Thr246. AA range:191-240

Specificity

Phospho-KCNQ2/3/4/5 (T217/246/223/251) Polyclonal Antibody detects endogenous levels of KCNQ2/3/4/5 protein only when phosphorylated at T217/246/223/251.

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.