Protein phosphatase-1 (PP1) is one of the main eukaryotic serine/threonine phosphatases. The protein encoded by this gene binds to the catalytic subunit of PP1, strongly inhibiting its activity. Ten related pseudogenes have been found throughout the human genome. Several splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
Catalog No
A1115
Reactivity
Human, Mouse, Rat
Applications
IHC-p, IF(paraffin section), ELISA
Modification
Phospho Specific
Source
Polyclonal Rabbit
Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
PPP1R2; IPP2; Protein phosphatase inhibitor 2; IPP-2
Molecular Weight (Da)
23015
Gene Name
PPP1R2
Protein Name
Protein phosphatase inhibitor 2
Human Gene ID
5504
Human Swiss Prot No.
P41236
Immunogen
The antiserum was produced against synthesized peptide derived from human PPP1R2 around the phosphorylation site of Ser120 and Ser121. AA range:86-135
Specificity
Phospho-IPP-2 (S120/S121) Polyclonal Antibody detects endogenous levels of IPP-2 protein only when phosphorylated at S120/S121.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Immunohistochemistry analysis of paraffin-embedded human heart, using PPP1R2 (Phospho-Ser120+Ser121) Antibody. The picture on the right is blocked with the phospho peptide.
Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using PPP1R2 (Phospho-Ser120+Ser121) Antibody