The protein encoded by this gene is a 47 kDa Cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease. [provided by RefSeq, Jul 2008]
Catalog No
A1171
Reactivity
Human, Mouse, Rat
Applications
WB, IHC-p, IF(paraffin section), ELISA
Modification
Phospho Specific
Source
Polyclonal Rabbit
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunohistochemistry analysis of paraffin-embedded human tonsil, using p47 phox (Phospho-Ser370) Antibody. The picture on the right is blocked with the phospho peptide.
Author:
Kaivon Assani, Chandra L. Shrestha, Frank Robledo-Avila,
Murugesan V. Rajaram, Santiago Partida-Sanchez, Larry S.
Schlesinger and Benjamin T. Kopp