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CREB-2 (Phospho-Ser245) Antibody
CREB-2 (Phospho-Ser245) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A7017
Reactivity:Human,Rat,Mouse
Applications:IHC,IF(paraffin section),ELISA
Modification:Phospho Specific
Source:Store at -20°C/1 year
Storage and Stability:

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CREB-2 (Phospho-Ser245) Antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using ATF4 (Phospho-Ser245) Antibody. The picture on the right is blocked with the phospho peptide.

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Product Details
Product Name
CREB-2 (Phospho-Ser245) Antibody
Description
activating transcription factor 4(ATF4) Homo sapiens This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2).The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication. [provid
Catalog No
A7017
Reactivity
Human, Rat, Mouse
Source
Polyclonal, Rabbit,IgG
Modification
Phospho Specific
Applications
IHC, IF(paraffin section), ELISA
Dilution
IHC 1:100 -300. ELISA: 1:10000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
ATF4; CREB2; TXREB; Cyclic AMP-dependent transcription factor ATF-4; cAMP-dependent transcription factor ATF-4; Activating transcription factor 4; Cyclic AMP-responsive element-binding protein 2; CREB-2; cAMP-responsive element-binding prot
Molecular Weight (Da or kDa)
Gene Name
ATF4
Protein Name
Cyclic AMP-dependent transcription factor ATF-4
Human Gene ID
468
Human Swiss Prot No.
P18848
Immunogen
The antiserum was produced against synthesized peptide derived from human ATF4 around the phosphorylation site of Ser245. AA range:212-261
Specificity
Phospho-CREB-2 (S245) Polyclonal Antibody detects endogenous levels of CREB-2 protein only when phosphorylated at S245.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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