Order your 5 sample sized mAbs for 77$ Order your Buy 1 get 1 on select products. Code: B1G1
Sign In/Register 0

We use cookies, check our Privacy Policies.

Products
Primary Antibodies
Chk2 (Phospho-Ser516) Antibody
Chk2 (Phospho-Ser516) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A7043
Reactivity:Human,Monkey
Applications:WB,ELISA
Modification:Phospho Specific
Source:Store at -20°C/1 year
Storage and Stability:

$205
# Datasheet #
# SDS #
Cell Cycle Proteins
Buy One Get One
#
#
#
#

Chk2 (Phospho-Ser516) Antibody

Western Blot analysis of various cells using Phospho-Chk2 (S516) Polyclonal Antibody.

Delivery
Contact Us
Telephone
408-747-0185
Fax
408-747-0145
Email
order@assaybiotech.com
Promotions
Product Details
Product Name
Chk2 (Phospho-Ser516) Antibody
Description
In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators.The protein encoded by this gene is a cell cycle checkpoint regulator and putative tumor suppressor. It contains a forkhead-associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage. When activated, the encoded protein is known to inhibit CDC25C phosphatase, preventing entry into mitosis, and has been shown to stabilize the tumor suppressor protein p53, leading to cell cycle arrest in G1. In addition, this protein interacts with and phosphorylates BRCA1, allowing BRCA1 to restore survival after DNA damage. Mutations in this gene have been linked with Li-Fraumeni syndrome, a highly penetrant familial cancer phenotype usually associated with inherited mutati
Catalog No
A7043
Reactivity
Human, Monkey
Source
Polyclonal, Rabbit,IgG
Modification
Phospho Specific
Applications
WB, ELISA
Dilution
WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
CHEK2; CDS1; CHK2; RAD53; Serine/threonine-protein kinase Chk2; CHK2 checkpoint homolog; Cds1 homolog; Hucds1; hCds1; Checkpoint kinase 2
Molecular Weight (Da or kDa)
Gene Name
CHEK2
Protein Name
Serine/threonine-protein kinase Chk2
Human Gene ID
11200
Human Swiss Prot No.
O96017
Immunogen
The antiserum was produced against synthesized peptide derived from human Chk2 around the phosphorylation site of Ser516. AA range:486-535
Specificity
Phospho-Chk2 (S516) Polyclonal Antibody detects endogenous levels of Chk2 protein only when phosphorylated at S516.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Related Products

Catalog No: N1292

β-actin Monoclonal Antibody(5B7)

Price/Quantity:
$184

Size:
100μL

Catalog No: N1293

GAPDH Monoclonal Antibody(2B8)

Price/Quantity:
$184

Size:
100μL

Catalog No: SA0001

HRP* Goat Anti Mouse IgG(H+L)

Price/Quantity:
$50

Size:
100μL

Catalog No: SA0002

HRP* Goat Anti Rabbit IgG(H+L)

Price/Quantity:
$50

Size:
100μL

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
    © 2024 AssayBiotech. All Rights Reserved.
    Follow Us
    Terms of Use Privacy Policy