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Primary Antibodies
Cofilin (Phospho-Ser3) Antibody
Cofilin (Phospho-Ser3) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A7047
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,IF,ELISA
Modification:Phospho Specific
Source:Store at -20°C/1 year
Storage and Stability:

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Cofilin (Phospho-Ser3) Antibody

Immunohistochemical analysis of paraffin-embedded Human lung cancer. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.

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Product Details
Product Name
Cofilin (Phospho-Ser3) Antibody
Description
cofilin 1(CFL1) Homo sapiens The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004],
Catalog No
A7047
Reactivity
Human, Mouse, Rat
Source
Polyclonal, Rabbit,IgG
Modification
Phospho Specific
Applications
WB, IHC, IF, ELISA
Dilution
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
CFL1; CFL; Cofilin-1; 18 kDa phosphoprotein; p18; Cofilin; non-muscle isoform
Molecular Weight (Da or kDa)
Gene Name
CFL1
Protein Name
Cofilin-1
Human Gene ID
3716
Human Swiss Prot No.
P23528
Immunogen
The antiserum was produced against synthesized peptide derived from human Cofilin around the phosphorylation site of Ser3. AA range:1-50
Specificity
Phospho-Cofilin (S3) Polyclonal Antibody detects endogenous levels of Cofilin protein only when phosphorylated at S3.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (3)
miR-29a/b/c function as invasion suppressors for gliomas by targeting CDC42 and predict the prognosis of patients. BRITISH JOURNAL OF CANCER Brit J Cancer. 2017 Aug;117(7):1036-1047 WB Human U87MG cell, U251 cell

Author: Available in link provided

Date of Publication : Available in link provided

Downregulation of glycine decarboxylase enhanced cofilin-mediated migration in hepatocellular carcinoma cells. FREE RADICAL BIOLOGY AND MEDICINE Free Radical Bio Med. 2018 May;120:1 WB Human MHCC97L cell, HCCLM3 cell,PLC cell, Hep3B cell

Author: Available in link provided

Date of Publication : Available in link provided

Eucalyptal A inhibits glioma by rectifying oncogenic splicing of MYO1B mRNA via suppressing SRSF1 expression. EUROPEAN JOURNAL OF PHARMACOLOGY Eur J Pharmacol. 2021 Jan;890:173669 WB Human LN229 cell,U87MG cell

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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