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Primary Antibodies
Cofilin (Phospho-Ser3) Antibody
Cofilin (Phospho-Ser3) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A7047
Reactivity:Human,Mouse,Rat
Applications:WB,IHC-p,IF(paraffin section),ELISA
Modification:Phospho Specific
Source:Polyclonal Rabbit
Storage and Stability:-20°C/1 year

$205
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Cofilin (Phospho-Ser3) Antibody

Western blot analysis of lysates from NIH/3T3 cells treated with paclitaxel 1uM 24hours, using Cofilin (Phospho-Ser3) Antibody. The lane on the right is blocked with the phospho peptide.

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Product Details
Product Name
Cofilin (Phospho-Ser3) Antibody
Description
cofilin 1(CFL1) Homo sapiens The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from Cytoplasm to nucleus.[supplied by OMIM, Apr 2004]
Catalog No
A7047
Reactivity
Human, Mouse, Rat
Applications
WB, IHC-p, IF(paraffin section), ELISA
Modification
Phospho Specific
Source
Polyclonal Rabbit
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
CFL1; CFL; Cofilin-1; 18 kDa phosphoprotein; p18; Cofilin; non-muscle isoform
Molecular Weight (Da)
18371
Gene Name
CFL1
Protein Name
Cofilin-1
Human Gene ID
3716
Human Swiss Prot No.
P23528
Immunogen
The antiserum was produced against synthesized peptide derived from human Cofilin around the phosphorylation site of Ser3. AA range:1-50
Specificity
Phospho-Cofilin (S3) Polyclonal Antibody detects endogenous levels of Cofilin protein only when phosphorylated at S3.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (3)
Eucalyptal A inhibits glioma by rectifying oncogenic splicing of MYO1B mRNA via suppressing SRSF1 expression

Author: Dan Hua, Qian Zhao, Yang Yu, Huan Yu, Lin Yu, Xuexia Zhou, Qian Wang, Cuiyun Sun, Cuijuan Shi, Wenjun Luo, Zhendong Jiang, Weiting Wang, Lingli Wang, Dongli Zhang, Shengan Tang, Shizhu Yu

Date of Publication : 2020-10-22

Downregulation of glycine decarboxylase enhanced cofilin-mediated migration in hepatocellular carcinoma cells

Author: Hao Zhuang, Qiang Li, Xinran Zhang, Xuda Ma, Zun Wang, Yun Liu, Xianfu Yi, Ruibing Chen, Feng Han, Ning Zhang, Yongmei Li

Date of Publication : 2018-03-07

miR-29a/b/c function as invasion suppressors for gliomas by targeting CDC42 and predict the prognosis of patients

Author: Shi, Cuijuan, Ren, Linlin, Sun, Cuiyun, Yu, Lin, Bian, Xiuwu, Zhou, Xuexia, Wen, Yanjun, Hua, Dan, Zhao, Shujun, Luo, Wenjun, Wang, Run, Rao, Chun, Wang, Qian, Yu, Shizhu

Date of Publication : 2017-08-08

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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