Sign In/Register 0

We use cookies, check our Privacy Policies.

Products
Primary Antibodies
JAK1 (Phospho-Tyr1022) Antibody
JAK1 (Phospho-Tyr1022) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A7125
Reactivity:Human,Mouse,Rat
Applications:IF/ICC,WB,IHC-p,ELISA
Modification:Phospho Specific
Source:Polyclonal Rabbit
Storage and Stability:-20°C/1 year

$205
# Datasheet #
# SDS #
Kinases and Phosphatases
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#
#

JAK1 (Phospho-Tyr1022) Antibody

Western Blot analysis of A549 cells using Phospho-JAK1 (Y1022) Polyclonal Antibody diluted at 1:500

Delivery
Contact Us
Telephone
408-747-0185
Fax
408-747-0145
Email
order@assaybiotech.com
Promotions
Product Details
Product Name
JAK1 (Phospho-Tyr1022) Antibody
Description
This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Catalog No
A7125
Reactivity
Human, Mouse, Rat
Applications
IF/ICC, WB, IHC-p, ELISA
Modification
Phospho Specific
Source
Polyclonal Rabbit
Dilution
IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
JAK1; JAK1A; JAK1B; Tyrosine-protein kinase JAK1; Janus kinase 1; JAK-1
Molecular Weight (Da)
131957
Gene Name
JAK1
Protein Name
Tyrosine-protein kinase JAK1
Human Gene ID
3716
Human Swiss Prot No.
P23458
Immunogen
The antiserum was produced against synthesized peptide derived from human JAK1 around the phosphorylation site of Tyr1022. AA range:988-1037
Specificity
Phospho-JAK1 (Y1022) Polyclonal Antibody detects endogenous levels of JAK1 protein only when phosphorylated at Y1022.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Related Products

Catalog No: N1292

β-actin Monoclonal Antibody(5B7)

Price/Quantity:
$200

Size:
100 ul

Catalog No: N1293

GAPDH Monoclonal Antibody(2B8)

Price/Quantity:
$200

Size:
100 ul

Catalog No: SA0001

HRP* Goat Anti Mouse IgG(H+L)

Price/Quantity:
$50

Size:
100μl

Catalog No: SA0002

HRP* Goat Anti Rabbit IgG(H+L)

Price/Quantity:
$50

Size:
100μl

Publications (9)
C6orf120 gene knockout in rats mitigates concanavalin A‑induced autoimmune hepatitis via regulating NKT cells

Author: Yuan-ni Wu, Rui Zhang, Xin-cheng Song, Xiao-xu Han, Jian Zhang, Xin Li

Date of Publication : 2021-12-01

Treadmill Exercise Attenuates Cerebral Ischemia–Reperfusion Injury by Promoting Activation of M2 Microglia via Upregulation of Interleukin-4

Author: Lu Juanjuan, Wang Jie, Yu Long, Cui Rong, Zhang Ying, Ding Hanqing, Yan Guofeng

Date of Publication : 2021-10-04

Paeoniflorin‐6′‐o‐benzene sulfonate (CP‐25) improves vasculitis through inhibiting IL‐17A/JAK/STAT3 signaling pathway in endothelial cells of HFD CIA rats

Author: Xiao-Yu Cai, Jing-Ru Ge, Li Xu, Fa-Qin Liang, Yue Zhu, Yu Tai, Xian-Zheng Zhang, Jin-Ling Shu, Dan Mei, Le Han, Chen Wang, Xiao-Yu Tang, Ling-Ling Zhang, Wei Wei

Date of Publication : 2020-10-02

Glycogen metabolism regulates macrophage-mediated acute inflammatory responses

Author: Ma, Jingwei, Wei, Keke, Liu, Junwei, Tang, Ke, Zhang, Huafeng, Zhu, Liyan, Chen, Jie, Li, Fei, Xu, Pingwei, Chen, Jie, Liu, Jincheng, Fang, Haiqing, Tang, Liang, Wang, Dianheng, Zeng, Liping, Sun, Weiwei, Xie, Jing, Liu, Yuying, Huang, Bo

Date of Publication : 2020-04-14

Novel paeonol derivatives: Design, synthesis and anti-inflammatory activity in vitro and in vivo

Author: Yang Sheng Hu, Xu Han, Pei Jing Yu, Ming Ming Jiao, Xin Hua Liu, Jing Bo Shi

Date of Publication : 2020-03-08

Herpes Simplex Virus 1 UL36USP Antagonizes Type I Interferon-Mediated Antiviral Innate Immunity

Author: Hui Yuan, Jia You, Hongjuan You, Chunfu Zheng

Date of Publication : 2018-10-01

Radiation alters PD-L1/NKG2D ligand levels in lung cancer cells and leads to immune escape from NK cell cytotoxicity via IL-6-MEK/Erk signaling pathway

Author: Ming Jing Shen,1,2 Li Jun Xu,1,2 Li Yang,1 Ying Tsai,1 Peter C. Keng,1 Yongbing Chen,2 Soo Ok Lee,1 and Yuhchyau Chen1

Date of Publication : n/a

Inhibition of IL-6-JAK/Stat3 signaling in castrationresistant prostate cancer cells enhances the NK cellmediated cytotoxicity via alteration of PD-L1/NKG2D ligand levels

Author: LiJun Xu1,2,†, XiaoDong Chen1,3,†, MingJing Shen1,2, Dong-Rong Yang2, Laifu Fang4, Guobin Weng3, Ying Tsai1, Peter C. Keng1, Yuhchyau Chen1 and Soo Ok Lee1

Date of Publication : n/a

Enhancing NK cell-mediated cytotoxicity to cisplatin-resistant lung cancer cells via MEK/Erk signaling inhibition

Author: Li Yang, MingJing Shen, Li Jun Xu, Xiaodong Yang, Ying Tsai, Peter C. Keng, Yuhchyau Chen & Soo Ok Lee

Date of Publication : n/a

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
    © 2024 AssayBiotech. All Rights Reserved.
    Follow Us
    Terms of Use Privacy Policy