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Primary Antibodies
JNK1/2/3 (Phospho-Tyr185) Antibody
JNK1/2/3 (Phospho-Tyr185) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A7129
Reactivity:Human,Mouse,Rat
Applications:IF/ICC,WB,IHC-p,ELISA
Modification:Phospho Specific
Source:Polyclonal Rabbit
Storage and Stability:-20°C/1 year

$205
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JNK1/2/3 (Phospho-Tyr185) Antibody

Western blot analysis of lysates from HepG2 cells treated with nocodazole 1ug/ml 16h, using SAPK/JNK (Phospho-Tyr185) Antibody. The lane on the right is blocked with the phospho peptide.

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Product Details
Product Name
JNK1/2/3 (Phospho-Tyr185) Antibody
Description
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spl
Catalog No
A7129
Reactivity
Human, Mouse, Rat
Applications
IF/ICC, WB, IHC-p, ELISA
Modification
Phospho Specific
Source
Polyclonal Rabbit
Dilution
IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
MAPK8; JNK1; PRKM8; SAPK1; SAPK1C; Mitogen-activated protein kinase 8; MAP kinase 8; MAPK 8; JNK-46; Stress-activated protein kinase 1c; SAPK1c; Stress-activated protein kinase JNK1; c-Jun N-terminal kinase 1; MAPK9; JNK2; PRKM9; SAPK1A; Mi
Molecular Weight (Da)
48296/48139/52585
Gene Name
MAPK8/9/10
Protein Name
Mitogen-activated protein kinase 8/9/10
Human Gene ID
5599/5601/5602
Human Swiss Prot No.
P45983/P45984/P53779
Immunogen
The antiserum was produced against synthesized peptide derived from human SAPK/JNK around the phosphorylation site of Tyr185. AA range:151-200
Specificity
Phospho-JNK1/2/3 (Y185) Polyclonal Antibody detects endogenous levels of JNK1/2/3 protein only when phosphorylated at Y185.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (3)
Proliferatins suppress lipopolysaccharide-induced inflammation via inhibition of the NF-κB and MAPK signaling pathways

Author: Qi-xuan Kuang, Qing-zhou Li, Li-rong Lei, Yu-mei Wang, Li-jun Huang, Yi-Fei Dai, Wan Peng, Ming-zhi Zhang, Dong Wang, Yu-cheng Gu, Yun Deng, Da-le Guo

Date of Publication : 2022-04-13

Amelioration of diabetic retinopathy in db/db mice by treatment with different proportional three active ingredients from Tibetan medicine Berberis dictyophylla F

Author: Rui Li, Xiaopeng Ai, Ya Hou, Xianrong Lai, Xianli Meng, Xiaobo Wang

Date of Publication : 2021-05-06

Targeting androgen receptor with ASC-J9 attenuates cardiac injury and dysfunction in experimental autoimmune myocarditis by reducing M1-like macrophage

Author: Wenhan Ma, Ya Wang, Shuai Lu, LianHua Yan, Fen Hu, ZhaoHui Wang

Date of Publication : 2017-02-27

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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