Order your 5 sample sized mAbs for 77$ Order your Buy 1 get 1 on select products. Code: B1G1
Sign In/Register 0

We use cookies, check our Privacy Policies.

Products
Primary Antibodies
LIMK-1 (Phospho-Thr508) Antibody
LIMK-1 (Phospho-Thr508) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A7140
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,IF,ELISA
Modification:Phospho Specific
Source:Store at -20°C/1 year
Storage and Stability:

$205
# Datasheet #
# SDS #
Kinases and Phosphatases
Buy One Get One
#
#
#
#
#
#
#
#
#
#

LIMK-1 (Phospho-Thr508) Antibody

Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using LIMK1 (Phospho-Thr508) Antibody

Delivery
Contact Us
Telephone
408-747-0185
Fax
408-747-0145
Email
order@assaybiotech.com
Promotions
Product Details
Product Name
LIMK-1 (Phospho-Thr508) Antibody
Description
There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is a serine/threonine kinase that regulates actin polymerization via phosphorylation and inactivation of the actin binding factor cofilin. This protein is ubiquitously expressed during development and plays a role in many cellular processes associated with cytoskeletal structure. This protein also stimulates axon growth and may play a role in brain development. LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cog
Catalog No
A7140
Reactivity
Human, Mouse, Rat
Source
Polyclonal, Rabbit,IgG
Modification
Phospho Specific
Applications
WB, IHC, IF, ELISA
Dilution
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
LIMK1; LIMK; LIM domain kinase 1; LIMK-1
Molecular Weight (Da or kDa)
Gene Name
LIMK1
Protein Name
LIM domain kinase 1
Human Gene ID
3984
Human Swiss Prot No.
P53667
Immunogen
The antiserum was produced against synthesized peptide derived from human LIMK1 around the phosphorylation site of Thr508. AA range:471-520
Specificity
Phospho-LIMK-1 (T508) Polyclonal Antibody detects endogenous levels of LIMK-1 protein only when phosphorylated at T508.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Related Products

Catalog No: N1292

β-actin Monoclonal Antibody(5B7)

Price/Quantity:
$184

Size:
100μL

Catalog No: N1293

GAPDH Monoclonal Antibody(2B8)

Price/Quantity:
$184

Size:
100μL

Catalog No: SA0001

HRP* Goat Anti Mouse IgG(H+L)

Price/Quantity:
$50

Size:
100μL

Catalog No: SA0002

HRP* Goat Anti Rabbit IgG(H+L)

Price/Quantity:
$50

Size:
100μL

Publications (1)
LIMK1/2 in the mPFC Plays a Role in Chronic Stress-Induced Depressive-Like Effects in Mice. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY 2020 Dec 29 WB Mouse 1:500 Hippocampus ， mPFC tissue

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
    © 2024 AssayBiotech. All Rights Reserved.
    Follow Us
    Terms of Use Privacy Policy