NFκB-p105 (Phospho-Ser907) Antibody (A7168)

NFκB-p105 (Phospho-Ser907) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A7168

Reactivity:Human,Rat,Mouse

Applications:WB,IHC,IF,IP,ELISA

Modification:Phospho Specific

Source:Store at -20°C/1 year

Storage and Stability:

Size:

Price/Quantity $205

Quantity:

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NFκB-p105 (Phospho-Ser907) Antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using NF-kappaB p105/p50 (Phospho-Ser907) Antibody.

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

Telephone

408-747-0185

Fax

408-747-0145

order@assaybiotech.com

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Product Details

Product Name

NFκB-p105 (Phospho-Ser907) Antibody

Description

nuclear factor kappa B subunit 1(NFKB1) Homo sapiens This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isof

Catalog No

A7168

Reactivity

Human, Rat, Mouse

Source

Polyclonal, Rabbit,IgG

Modification

Phospho Specific

Applications

WB, IHC, IF, IP, ELISA

Dilution

WB 1:500 - 1:2000. IHC 1:100 - 1:300. Immunoprecipitation: 2-5 ug:mg lysate. ELISA: 1:20000.. IF 1:50-200

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Storage and Stability

Store at -20°C/1 year

Other Name

NFKB1; Nuclear factor NF-kappa-B p105 subunit; DNA-binding factor KBF1; EBP-1; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

Molecular Weight (Da or kDa)

Gene Name

NFKB1

Protein Name

Nuclear factor NF-kappa-B p105 subunit

Human Gene ID

4790

Human Swiss Prot No.

P19838

Immunogen

The antiserum was produced against synthesized peptide derived from human NF-kappaB p105/p50 around the phosphorylation site of Ser907. AA range:874-923

Specificity

Phospho-NFκB-p105 (S907) Polyclonal Antibody detects endogenous levels of NFκB-p105 protein only when phosphorylated at S907.

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.