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Primary Antibodies
NFκB-p65 (Phospho-Ser468) Antibody
NFκB-p65 (Phospho-Ser468) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A7170
Reactivity:Human,Mouse,Rat
Applications:WB,IHC-p,IF(paraffin section),IP,ELISA
Modification:Phospho Specific
Source:Polyclonal Rabbit
Storage and Stability:-20°C/1 year

$205
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NFκB-p65 (Phospho-Ser468) Antibody

Western blot analysis of lysates from Jurkat cells and 293 cells, using NF-kappaB p65 (Phospho-Ser468) Antibody. The lane on the right is blocked with the phospho peptide.

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Product Details
Product Name
NFκB-p65 (Phospho-Ser468) Antibody
Description
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the Cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Catalog No
A7170
Reactivity
Human, Mouse, Rat
Applications
WB, IHC-p, IF(paraffin section), IP, ELISA
Modification
Phospho Specific
Source
Polyclonal Rabbit
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunoprecipitation: 2-5 ug/mg lysate. ELISA: 1/20000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
RELA; NFKB3; Transcription factor p65; Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3
Molecular Weight (Da)
60219
Gene Name
RELA
Protein Name
Transcription factor p65
Human Gene ID
5970
Human Swiss Prot No.
Q04206
Immunogen
The antiserum was produced against synthesized peptide derived from human NF-kappaB p65 around the phosphorylation site of Ser468. AA range:435-484
Specificity
Phospho-NFκB-p65 (S468) Polyclonal Antibody detects endogenous levels of NFκB-p65 protein only when phosphorylated at S468.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (6)
Sacubitril/Valsartan Alleviates Experimental Autoimmune Myocarditis by Inhibiting Th17 Cell Differentiation Independently of the NLRP3 Inflammasome Pathway

Author: Wei Liang, Bai-Kang Xie, Pei-Wu Ding, Min Wang, Jing Yuan, Xiang Cheng, Yu-Hua Liao, Miao Yu

Date of Publication : 2021-09-15

CD137 Signaling Promotes Endothelial Apoptosis by Inhibiting Nrf2 Pathway, and Upregulating NF-κB Pathway

Author: Geng Tianxin, Yan Yang, Zhang Yue, Xu Liangjie, Zang Guangyao, Yan Jin Chuan

Date of Publication : 2020-06-06

Rhein protects against barrier disruption and inhibits inflammation in intestinal epithelial cells

Author: Shen Zhuang, Jia Zhong, Qilv Zhou, Yuan Zhong, Ping Liu, Zhongjie Liu

Date of Publication : 2019-04-02

Soybean Glycinin- and β-Conglycinin-Induced Intestinal Damage in Piglets via the p38/JNK/NF-κB Signaling Pathway

Author: Chenglu Peng, Chengming Cao, Mengchu He, Yingshuang Shu, Xuebing Tang, Yuanhong Wang, Yu Zhang, Xiaodong Xia, Yu Li, Jinjie Wu

Date of Publication : 2018-08-24

CD137 Regulates NFATc1 Expression in Mouse VSMCs through TRAF6/NF-κB p65 Signaling Pathway

Author: Yan Jinchuan, Yin Yunjie, Zhong Wei, Wang Cuiping, Wang Zhongqun

Date of Publication : 2015-10-27

Chronic glucocorticoids exposure enhances neurodegeneration in the frontal cortex and hippocampus via NLRP-1 inflammasome activation in male mice

Author: Wen Hu, Yaodong Zhang, Wenning Wu, Yanyan Yin, Dake Huang, Yuchan Wang, Weiping Li, Weizu Li

Date of Publication : 2015-10-03

Primary Antibodies

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    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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