Order your 5 sample sized mAbs for 77$ Order your Buy 1 get 1 on select products. Code: B1G1
Sign In/Register 0

We use cookies, check our Privacy Policies.

Products
Primary Antibodies
p21 (Phospho-Thr145) Antibody
p21 (Phospho-Thr145) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A7175
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,IF,ELISA
Modification:Phospho Specific
Source:Store at -20°C/1 year
Storage and Stability:

$205
# Datasheet #
# SDS #
Cell Cycle Proteins
Buy One Get One
#
#
#
#
#
#

p21 (Phospho-Thr145) Antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using p21 Cip1 (Phospho-Thr145) Antibody. The picture on the right is blocked with the phospho peptide.

Delivery
Contact Us
Telephone
408-747-0185
Fax
408-747-0145
Email
order@assaybiotech.com
Promotions
Product Details
Product Name
p21 (Phospho-Thr145) Antibody
Description
This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-cyclin-dependent kinase2 or -cyclin-dependent kinase4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen, a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of cyclin-dependent kinase2, and may be instrumental in the execution of apoptosis following caspase activation. Mice that lac
Catalog No
A7175
Reactivity
Human, Mouse, Rat
Source
Polyclonal, Rabbit,IgG
Modification
Phospho Specific
Applications
WB, IHC, IF, ELISA
Dilution
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
CDKN1A; CAP20; CDKN1; CIP1; MDA6; PIC1; SDI1; WAF1; Cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6; p21;
Molecular Weight (Da or kDa)
18kD
Gene Name
CDKN1A
Protein Name
Cyclin-dependent kinase inhibitor 1
Human Gene ID
1026
Human Swiss Prot No.
P38936
Immunogen
The antiserum was produced against synthesized peptide derived from human p21 Cip1 around the phosphorylation site of Thr145. AA range:111-160
Specificity
Phospho-p21 (T145) Polyclonal Antibody detects endogenous levels of p21 protein only when phosphorylated at T145.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Related Products

Catalog No: N1292

β-actin Monoclonal Antibody(5B7)

Price/Quantity:
$184

Size:
100μL

Catalog No: N1293

GAPDH Monoclonal Antibody(2B8)

Price/Quantity:
$184

Size:
100μL

Catalog No: SA0001

HRP* Goat Anti Mouse IgG(H+L)

Price/Quantity:
$50

Size:
100μL

Catalog No: SA0002

HRP* Goat Anti Rabbit IgG(H+L)

Price/Quantity:
$50

Size:
100μL

Publications (2)
Synergetic and Antagonistic Molecular Effects Mediated by the Feedback Loop of p53 and JNK between Saikosaponin D and SP600125 on Lung Cancer A549 Cells. MOLECULAR PHARMACEUTICS Mol Pharmaceut. 2018;15(11):4974–4984 WB Human 1:1000 A549 cell

Author: Available in link provided

Date of Publication : Available in link provided

Hey1 promotes migration and invasion of melanoma cells via GRB2/PI3K/AKT signaling cascade. Journal of Cancer J Cancer. 2021; 12(23): 6979–6988 WB Human 1:1000 A375 cell

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
    © 2025 AssayBiotech. All Rights Reserved.
    Follow Us
    Terms of Use Privacy Policy